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Research

Dante Labs Unveils 1,000 Patient Epilepsy Whole Genome Study to Advance Research and Therapies for Patients With Epilepsy

A Global Epilepsy Whole Genome Study will sequence 1,000 patients diagnosed with epilepsy over the next nine months, further advancing the research and development of gene therapies for epilepsy.
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App Aids in Diagnosing Pediatric Epilepsy

A web-based application could help doctors diagnose epilepsy in children following an initial paroxysmal event with little information to differentiate epilepsy from other possibilities.
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Autism Spectrum Disorders and Epilepsy in Children: A Commentary on the Occurrence of Autism in Epilepsy; How It Can Present Differently and the Challenges Associated With Diagnosis

This paper examined the issues and challenges of diagnosing autism in a population with a high-risk of epilepsy.
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Effects of valproate (Depakote), lamotrigine (Lamictal), and levetiracetam (Keppra) monotherapy on bone health in newly diagnosed adult patients with epilepsy

The aim of this study was to evaluate the effects of valproate (VPA), lamotrigine (LTG), and levetiracetam (LEV) on bone turnover and bone mineral density (BMD) in newly diagnosed adult patients with epilepsy...Read More
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Characteristics and Treatment Outcomes of Newly Diagnosed Epilepsy in Older People: A 30-Year Longitudinal Cohort Study

This study sought to describe the clinical characteristics and evaluate the long-term treatment outcomes in older people with newly diagnosed epilepsy over the past 30 years.
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Genetic Diagnoses in Epilepsy: The Impact of Dynamic Exome Analysis in a Pediatric Cohort

The data argue for early consideration of WES with iterative reanalysis for patients with epilepsy, particularly those with DEE or epilepsy with intellectual disability.
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Fifty-Year Follow-Up of Childhood Research Reveals a Balancing Act Between Managing and Not Being Restricted by Epilepsy

This long-term follow-up over a 50-year life-span of persons who received childhood diagnoses of epilepsy suggests that the consequences for education, work, and leisure activities were few.
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Impact of Diagnostic Delay on Seizure Outcome in Newly Diagnosed Focal Epilepsy

Patients with focal epilepsy experience significant delays in diagnosis even in developed countries, especially with seizure types other than tonic-clonic seizures.
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Diagnosing Cognitive Disorders in Older Adults With Epilepsy

To characterize the nature and prevalence of cognitive disorders in older adults with temporal lobe epilepsy (TLE) and compare their cognitive profiles to patients with amnestic mild cognitive impairment (ie, aMCI).
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Prevalence and Trajectories of Depressive Symptoms Among Mothers of Children with Newly Diagnosed Epilepsy: A Longitudinal 10-Year Study

A substantial proportion of mothers of children with epilepsy are at risk for depression, and this risk is stable over the long term.
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