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March 19, 2024

Genotype–Phenotype Associations in Individuals with SCN1A-Related Epilepsies

Understanding genotype–phenotype associations in SCN1A-related epilepsies is critical for early diagnosis and management.

March 19, 2024

Study Data on Lacosamide and Pregnancy

Most pregnancies with LCM exposure resulted in healthy live births, and no new medication concerns were identified. These findings should be interpreted with caution, as additional data are needed to fully evaluate the safety profile of LCM in pregnancy.

March 19, 2024

Patterns Across Epilepsy Syndromes Study

These findings highlight the cerebellum as a potential target for therapeutic intervention in epilepsy and underscore the importance of incorporating the cerebellum into neurobiological models of epilepsy. 

March 19, 2024

Study Looks at the Burden of Illness of Lennox–Gastaut Syndrome on Patients, Caregivers, and Society

A high burden of LGS on individuals, caregivers, and healthcare systems was identified. The burden may be alleviated by reducing the clinical symptoms.

March 19, 2024

Epilepsy and the Risk of COVID-19-Related Hospitalization and Death

Study results may have implications for prioritizing future COVID-19 treatments and vaccinations for people with epilepsy. The study shows the importance of characterizing this risk to inform patients and for future health and care planning.

March 19, 2024

Post-Traumatic Epilepsy Associated with Long-Term Dementia Risk

Dementia risk was significantly higher with PTE than with epilepsy/seizure or head injury alone. These results highlight the significance of prevention of head injuries and PTE following these injuries.

March 11, 2024

CURE Epilepsy Discovery: FCD Genes in Epilepsy, One Piece of the Mosaic

2017 CURE Epilepsy grantee Dr. Jack Parent and his team designed a novel system using human neurons grown in a dish to discover the genes behind focal cortical dysplasia (FCD), a common cause of intractable epilepsy.

February 14, 2024

Death Rate Higher than Expected for Patients with Functional, Nonepileptic Seizures

The death rate for patients with functional, nonepileptic seizures is higher than expected, with a rate comparable to epilepsy and severe mental illness, a Michigan Medicine-led study finds.

February 14, 2024

Fintepla Safely Reduces Seizures in Children Younger than 2, Study Finds

Treatment with Fintepla (fenfluramine) appeared to be reasonably safe and lower seizure frequency in five children with Dravet syndrome who started on the therapy before they were two years old.

February 14, 2024

Revolutionary 3D-Printed Brain Tissue Mimics Human Function

"This could be a hugely powerful model to help us understand how brain cells and parts of the brain communicate in humans,” says Su-Chun Zhang, professor of neuroscience and neurology at UW–Madison’s Waisman Center.

February 14, 2024

Infantile Spasms: Speeding Referrals for All Infants

A recent study found that Black children and children with public insurance are less likely to receive a standard treatment course for IS.

January 12, 2024

Seizures Identified as Potential Cause of Sudden Unexplained Deaths in Children

“These findings show that seizures are much more common than patients’ medical histories suggest, and that further research is needed to determine if seizures are frequent occurrences in sleep-related deaths in toddlers, and potentially in infants, older children, and adults,”

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