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Calvin’s Story
Personal StoryCalvin is my hero, my little muse, my inspiration and the one who makes me want to be a better person every day.
Charlie’s Story
Personal StoryFor me, the hardest part of Charlie’s seizures was seeing his eyes. You don’t hear much about the eyes.
Infantile Spasms: Mechanisms and Consequences as Therapeutic Targets
Grants AwardedThis commentary discusses three aspects of IESS intended to raise fundamental clinical and mechanistic issues to afford greater understanding of the syndrome – nomenclature, EEG findings, and selected emerging animal models that might shed light on IESS pathophysiology and guide therapy development.
A Novel Transposon Causes Focal Cortical Dysplasia
Grants AwardedIf our data is correct, the future for patients with FMCD may include targeted therapy to cure HPV16 infection that could lead to truly new and successful treatment strategies with improved efficacy (“no seizures”) and diminished morbidity (“no side effects”).
Molecular Mechanisms Of Epilepsy-Causing Mutations In The IKM Channel: Anti-Epileptic Effect Of Polyunsaturated Fatty Acids (PUFAs) Variants Rene Barro Soria, Phd
Grants AwardedThe goals of the present research project are a) to define the molecular basis of voltage activation of IKM channels, to understand the mechanisms by which epilepsy causing mutations affect IKM channels function and b) to design new drugs for the treatment of these IKM channelopathies.