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Gianna’s Story
Personal StoryAs I pray every night for Gianna’s seizures to stop, I also pray for a cure—and for much comfort for the millions of people and their families affected by epilepsy.
Responsive Neurostimulation (RNS)
Epilepsy ExplainedIn this Epilepsy Explained video, we explore Responsive Neurostimulation (RNS) within the context of Epilepsy Treatments and Therapies, explaining what it is, who should consider getting one, how it differs from other neuromodulation devices.
Stem Cells & Epilepsy: A New Therapeutic Approach for Treating Drug-Resistant Epilepsy
WebinarThis webinar will discuss a pioneering neural cell therapy approach that could provide a novel treatment for drug-resistant focal epilepsy.Vigabatrin
MedicationsVigabatrin is FDA-approved as add-on therapy for treating refractory focal-onset impaired awareness seizures in patients 2 years of age and older.Tiagabine
MedicationsTiagabine has been approved by the FDA as adjunctive therapy in the treatment of focal seizures in both adults and children over the age of 12Perampanel
MedicationsPerampanel (Fycompa) is FDA-approved to treat focal-onset seizures—with or without secondary generalization—in patients age 4 and older.Gabapentin
MedicationsGabapentin is FDA-approved as an add-on treatment for focal-onset seizures, helping improve seizure control alongside other therapies.
Preclinical Testing of Oral KCC2 Potentiator Drug AXN-006-01-3 to Rescue Phenobarbital-Resistant Neonatal Seizures
Grants AwardedThis study will generate key data showing that AXONIS’ brain-penetrating, KCC2-potentiating drug can treat refractory neonatal seizures and prevent epileptogenesis in a neonatal phenobarbital-resistant mouse model of HIE.
Preclinical IND Enabling Studies of TrkB Peptide
Grants AwardedThe goal of this translational research project is to conduct key studies to advance pY816 to human clinical trials for TLE.