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One Family, Two Different Epilepsy Diagnoses

Podcast SeriesThis week on Seizing Life® we speak with Mary and Tom Nugent, parents of 3 young men, two of whom have grown-up with epilepsy. With one son severely impacted from infancy and another diagnosed at the age of 9, the Nugents have experienced the vastly different impacts of epilepsy in the microcosm of their own household.

Autism Spectrum Disorders and Epilepsy in Children: A Commentary on the Occurrence of Autism in Epilepsy; How It Can Present Differently and the Challenges Associated With Diagnosis

ResearchThis paper examined the issues and challenges of diagnosing autism in a population with a high-risk of epilepsy.

Effects of valproate (Depakote), lamotrigine (Lamictal), and levetiracetam (Keppra) monotherapy on bone health in newly diagnosed adult patients with epilepsy

ResearchThe aim of this study was to evaluate the effects of valproate (VPA), lamotrigine (LTG), and levetiracetam (LEV) on bone turnover and bone mineral density (BMD) in newly diagnosed adult patients with epilepsy...Read More

Characteristics and Treatment Outcomes of Newly Diagnosed Epilepsy in Older People: A 30-Year Longitudinal Cohort Study

ResearchThis study sought to describe the clinical characteristics and evaluate the long-term treatment outcomes in older people with newly diagnosed epilepsy over the past 30 years.

Genetic Diagnoses in Epilepsy: The Impact of Dynamic Exome Analysis in a Pediatric Cohort

ResearchThe data argue for early consideration of WES with iterative reanalysis for patients with epilepsy, particularly those with DEE or epilepsy with intellectual disability.

Fifty-Year Follow-Up of Childhood Research Reveals a Balancing Act Between Managing and Not Being Restricted by Epilepsy

ResearchThis long-term follow-up over a 50-year life-span of persons who received childhood diagnoses of epilepsy suggests that the consequences for education, work, and leisure activities were few.

Impact of Diagnostic Delay on Seizure Outcome in Newly Diagnosed Focal Epilepsy

ResearchPatients with focal epilepsy experience significant delays in diagnosis even in developed countries, especially with seizure types other than tonic-clonic seizures.

Diagnosing Cognitive Disorders in Older Adults With Epilepsy

ResearchTo characterize the nature and prevalence of cognitive disorders in older adults with temporal lobe epilepsy (TLE) and compare their cognitive profiles to patients with amnestic mild cognitive impairment (ie, aMCI).

Prevalence and Trajectories of Depressive Symptoms Among Mothers of Children with Newly Diagnosed Epilepsy: A Longitudinal 10-Year Study

ResearchA substantial proportion of mothers of children with epilepsy are at risk for depression, and this risk is stable over the long term.

Study Examines the Potential Role of Next-Generation Sequencing for Genetic Diagnoses of Epilepsy Presenting in the First 2 Years of Life

ResearchThe aim of this study is to describe children with epilepsy onset before 2 years of age, and to explore to what degree whole exome and whole genome sequencing (WES/WGS) can help reveal a molecular genetic diagnosis.