CURE - Citizens United for Research in Epilepsy It's Time We Found a CURE CURE Epilepsy Research

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CURE Epilepsy

Since its inception in 1998, CURE has raised more than $43 million to fund epilepsy research and other initiatives that will lead the way to cures for the epilepsies. CURE awards grants for novel research projects to prevent epilepsy related to post-traumatic epilepsy, advancing the search for a cure, eliminating CURE Researchtreatment side effects, and reversing deficits caused by frequent seizures. CURE funds grants for young and established investigators and to date has awarded more than 200 cutting-edge projects in 15 countries around the world.

In 2002, CURE established the first Sudden Unexpected Death in Epilepsy (SUDEP)-targeted research program. The leader in research to understand and eliminate SUDEP, CURE has awarded 27 SUDEP grants, totaling more than $3 million.

In 2007, CURE established the first-ever Prevention of Epilepsy After Traumatic Brain Injury Award; epilepsy prevention is currently a priority area in the annual CURE Epilepsy Award. For many soldiers suffering TBI on the battlefield, epilepsy will be a long-term consequence.

In 2010, CURE took up another unprecedented initiative to impact epilepsy research and awareness by publishing its State of Research in the Epilepsies Report. The analyses conducted in the report confirm the challenges in advancing research in this critical area. Based on the findings in the report CURE embarked on an aggressive strategy to accelerate progress in research aimed at discovering a cure. Key elements of the strategy include re-balancing and intensifying research efforts that will enhance our understanding of the underlying mechanisms of epilepsy, and an insistence upon active collaboration between researchers.

In 2012, the CURE launched the Infantile Spasms (IS) Research Initiative to accelerate the understanding of IS and advance a new, innovative therapy into the clinic. With $3.5 million in grant funding to date, six teams of investigators are focusing on cutting-edge research for IS, a rare childhood epilepsy syndrome. The project involves investigators at multiple institutions around the country and uniquely promotes a multidisciplinary, team science approach that encourages collaboration between researchers. 

In 2015, CURE launched a new signature program, the Epilepsy Genetics Initiative (EGI). With an initial $1 million in funding, EGI has launched a comprehensive, interactive database where patients’ genetic data is collected and repeatedly analyzed in an effort to identify a cause for their epilepsy. These data will also be made available to epilepsy researchers in an effort to find new causes of epilepsy and use these findings to advance research towards precision therapies. EGI brings patients, medical professionals and researchers together in a mutually beneficial way to advance how we understand the impact of genetics in epilepsy and to help create a culture of personalized medicine for people with epilepsy.

CURE also began a new research program in 2015 dedicated to epilepsy research in veterans with traumatic brain injury with the help of a $10 million grant over five years from the Department of Defense, Psychological Health and Traumatic Brain Injury Research Program. The program will support a team approach to researching the prevention and treatment of Post-Traumatic Epilepsy (PTE).

Greater funding for these research efforts is, of course, critical to finding a cure—these efforts cannot be successful without a significant investment. You can help by donating today or writing your representatives in Congress to share your personal stories and your commitment to ensuring that funding epilepsy research is a priority.

Tireless in its efforts and determination, CURE won’t stop until a cure is found for every person who is affected by epilepsy.  


*This page was updated on January 21, 2016.



CURE For questions, please contact Liz Higgins at the CURE office, 312.255.1801, or email

CURE Epilepsy
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