CURE Epilepsy was founded in 1998 by a group of parents desperate for answers to save their children. Since then, CURE Epilepsy has led a dramatic shift in the epilepsy research community from simply treating seizures to enhancing understanding of underlying mechanisms and causes so that cures and preventative strategies can be found.
From creating groundbreaking initiatives on SUDEP and genetics, to developing a team-science approach to study post-traumatic epilepsy for the U.S. Department of Defense, we remain laser-focused on funding research to find the cures for epilepsy.
Hear from both researchers and families affected by epilepsy to learn about some of the issues affecting the epilepsy community–and how CURE Epilepsy is working to solve them.
Over one-third of all epilepsy is treatment-resistant. In 2011, using a CURE Epilepsy Challenge Award funded by the Julie’s Hope Award, Dr. Brian Litt was able to break new ground in the field of implantable devices to detect and treat epilepsy. Dr. Litt shares the tangible results of his research and breakthroughs that continue today as a result of this grant.
Channing Seideman shares her journey with refractory or treatment-resistant epilepsy, how it impacts her day-to-day, and the research that Dr. Detlev Boison is doing to understand how to block the enzyme that prevents the brain’s natural seizure-terminator, adenosine, from working properly.
Epilepsy may be acquired through injury, infection, or other factors affecting the brain. Alex, son of former CURE Epilepsy Board Member Paul Heldman, acquired epilepsy at age 19 after a brain infection. Dr. James Gugger explains how someone like Alex can acquire epilepsy, and that research into how epilepsy begins is crucial to finding a cure.
Between 2000 and 2020, over 400,000 active service members sustained a traumatic brain injury (TBI). One of these service members was Pat Horan, whose TBI became PTE. Dr. Pavel Klein is doing research as part of the CURE Epilepsy PTE Initiative to understand who is more at risk of their TBI becoming PTE and pave the way to develop therapies to prevent this from occurring.
Hear from Cameron Boyce’s family, who only learned about sudden unexpected death in epilepsy (SUDEP) after Cameron passed away at the age of 20, and Dr. Ann Poduri, who discusses potential ways to mitigate the risk of SUDEP.
Dr. Daniel Lowenstein describes the urgency of finding a cure for epilepsy and how research will lead us to that cure.
One in 26 Americans will develop epilepsy in their lifetime and 65 million people worldwide are affected by epilepsy. These are the “faces of epilepsy.”
Thanks to technological advancements, we know there are hundreds of genes implicated in different pediatric epilepsies. Jessica Rosini talks about her son Dominic, whose epilepsy appeared before his 3rd birthday. He is counting on researchers like Dr. Gemma Carvill, who is developing precision medicine to cure rare, genetic forms of epilepsy like Dominic’s.
Three in 10 epilepsy patients don’t respond to medication. Nathan Bliss describes childhood with his brother Charles, who has tried hundreds of treatments for Lennox-Gastaut syndrome, a severe, treatment-resistant epilepsy. Dr. Brenda Porter highlights recent advances to help make Charles and others like him seizure-free.