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August 8, 2022

Seizure-Related Injuries in Adults: A Prospective Case-Controlled Study on Risk Factors, Seizure Severity and Quality of Life

The occurrence of seizure-related injuries suffered throughout the lifespan and recurrent injuries in the previous year were high. Injuries were significantly associated with epilepsy variables, the perception of greater severity of seizures and risky activities.

August 4, 2022

Impact of Development and Recent-Onset Epilepsy on Language Dominance

Our results demonstrate that while language remained largely left-lateralized in children recently diagnosed with epilepsy, the impact of seizure duration depended on age of onset indicating that timing of developmental and disease factors are important in determining language dominance.

August 4, 2022

Epidemiology and Disease Burden of Tuberous Sclerosis Complex in France: a Population-Based Study Based on National Health Insurance Data

Tuberous sclerosis complex (TSC) is a rare multisystem disorder, often associated with epilepsy. This retrospective study aimed to identify patients with TSC, including those with epilepsy, from a French healthcare claims database, and to report incidence, prevalence, and healthcare costs and resource utilization.

August 4, 2022

CURE Epilepsy Update August 2022

Seizure Dog Awareness Month, TikTok, back to school planning, and more in this exciting CURE Epilepsy Update.

August 2, 2022

Decision Making in Stereotactic Epilepsy Surgery

This article articulates and illustrates the full framework for how epilepsy patients are considered for surgical intervention, with particular attention given to stereotactic approaches.

August 2, 2022

Epilepsy Management During Difficult Times

We discuss the consequences of natural disasters, conflicts, economic sanctions, and focus in greater detail on lessons learnt during the COVID-19 pandemic. We also discuss possible mitigation procedures, focusing in particular on the application of telemedicine to epilepsy care. Finally, we underline the need for governments, healthcare authorities, and international organizations to improve their preparedness to deal with exceptional situations that may arise in the future.

August 1, 2022

Post-Operative Progression of Brain Metastasis is Associated with Seizures

Postoperative progression of brain metastases quadrupled the risk of seizures, therefore vigorous follow-up may be useful to identify tumor progression and gauge the risk of seizures. The identification of patients at high seizure risk may have implications on treatment decisions and influence aspects of daily life.

August 1, 2022

Genetic Interaction Between Scn8a and Potassium Channel Genes Kcna1 and Kcnq2

We tested the hypothesis that reducing expression of Scn8a would compensate for loss-of-function mutations of Kcna1 or Kcnq2. Scn8aexpression was reduced by administration of an antisense oligonucleotide (ASO).

July 29, 2022

Seizures in Young Stroke Survivors Double Dementia Risk

The onset of seizures in young stroke survivors is associated with more than a doubled risk for developing dementia, according to a study published July 26 in Neurology.

July 28, 2022

CURE Epilepsy Discovery: Identifying a Promising Novel Treatment for Infantile Spasms

Standard treatments for IS work in only 50% of patients and can have severe side effects. The need for additional effective therapies drove Dr. Swann and his team to explore a more effective treatment with fewer or, ideally, no side effects.

July 28, 2022

Atrophy of the Hippocampal CA1 Subfield Relates to Long-Term Forgetting in Focal Epilepsy

Patients with focal epilepsy had lower intelligence quotients and route recall scores at 10 minutes than controls. The focal epilepsy group had smaller volumes of both the right and left hippocampal tails than the control group, but there were no significant group differences for the volumes of the whole hippocampus or other hippocampal subfields.

July 28, 2022

Antiseizure Medication and Perceived “Fair” Cost Allocation: a Factorial Survey Among Neurologists, Persons with Epilepsy, Their Relatives and a Control Group

As resources are limited in modern healthcare systems, the decision on the allocation of expensive drugs can be supported by a public consent. This study examines how various factors influence subjectively perceived “fair” pricing of antiseizure medication (ASM) among four groups including physicians, persons with epilepsy (PWE), their relatives and a control group.

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