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October 23, 2020

Can Changes in Gut Microbiota Composition Be Used as a Marker of How Well the Ketogenic Diet Works in Patients With Drug-Resistant Epilepsy?

To answer the question posed in the title of the manuscript, the authors critically examined the connection between ketogenic diet (KD), gut microbiota (GM), and epilepsy.

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October 23, 2020

SUDEP Action Day 2020

Annually on October 23, the global epilepsy community comes together for SUDEP Action Day, an international event to raise awareness about Sudden Unexpected Death in Epilepsy (SUDEP).

October 22, 2020

Review: Utilizing the Brain Activity Called High Frequency Oscillations as an EEG Biomarker to Predict the Development of Epilepsy and Seizures

The study of high frequency oscillations (HFO) [a type of brain activity] in the electroencephalogram (EEG) as biomarkers of epileptic activity has merely focused on their spatial location and relationship to the epileptogenic zone.

October 22, 2020

CURE Epilepsy Discovery: Epilepsy Surgery May Be Beneficial in Reducing SUDEP

This CURE Epilepsy-funded study provides evidence for the beneficial effects of epilepsy surgery in reducing overall mortality including SUDEP.

October 21, 2020

Seizure-Related Injuries in Inadequately Treated Epilepsy Patients: A Case-Control Study

This study's purpose was to compare epilepsy-related injuries in untreated or inadequately treated patients and patients on adequate treatment. Learn more.

October 21, 2020

Nasal Pain as an Aura: Amygdala Origin?

Nasal pain, as an epileptic aura, has been poorly recognized. This study aims to demonstrate clinical features of patients with epilepsy who have nasal pain as an aura.

October 20, 2020

Cenobamate (Xcopri): Can Preclinical and Clinical Evidence Provide Insight Into Its Mechanism of Action?

Approximately one-third of people living with epilepsy are unable to obtain seizure control with the currently marketed antiseizure medications (ASMs), creating a need for novel therapeutics with new mechanisms of action.

October 20, 2020

Focal Epilepsy Often Overlooked

Having subtler symptoms, a form of epilepsy that affects only one part of the brain often goes undiagnosed long enough to cause unexpected seizures that contribute to car crashes, a new study finds.

October 19, 2020

Study Findings Suggest Animal Model Replicates Key Molecular Features of Human Drug-Resistant Temporal Lobe Epilepsy

Pharmacoresistance and the lack of disease?modifying actions of current antiseizure drugs persist as major challenges in the treatment of epilepsy. The aim of the present study was to compare the molecular landscape of the intra?amygdala kainic acid model of status epilepticus in mice with findings in resected brain tissue from patients with drug?resistant temporal lobe epilepsy (TLE).

October 19, 2020

Where Have the Children With Epilepsy Gone? An Observational Study of Seizure-Related Accesses to Emergency Department at the Time of COVID-19

The COVID-19 pandemic and related lockdown measures drastically changed health care and emergency services utilization. This study evaluated trends in emergency department (ED) access for seizure-related reasons in the first 8 weeks of lockdown in Italy.

October 19, 2020

Review: Current Knowledge of SLC6A1-Related Neurodevelopmental Disorders

Advances in gene discovery have identified genetic variants in the solute carrier family 6 member 1 (SLC6A1) gene as a monogenic cause of neurodevelopmental disorders, including epilepsy with myoclonic atonic seizures, autism spectrum disorder, and intellectual disability.

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October 18, 2020

We are now CURE Epilepsy

Formerly-known as Citizens United for Research in Epilepsy (CURE), we have rebranded to CURE Epilepsy.

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