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January 18, 2019

Safety and Effectiveness of Stereotactic Laser Ablation for Epileptogenic Cerebral Cavernous Malformations

Magnetic resonance thermography-guided stereotactic laser ablation was found to be an effective alternative to open surgery for epileptogenic cerebral cavernous malformations.

January 18, 2019

Diagnostic Yield of Genetic Tests in Epilepsy: A Meta-Analysis and Cost-Effectiveness Study

Whole-exome sequencing and epilepsy panel are the most cost-effective genetic tests for epilepsy, and, for a broad population of patients with unexplained epilepsy, this research supports starting with these tests.

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January 17, 2019

CURE Discovery: Predicting Acquired Epilepsy Following a Brain Infection

Researchers identify a possible biomarker, detectable as early as 14 weeks before the first seizure, for predicting who will develop epilepsy following infection with malaria.

January 17, 2019

Prevalence and Trajectories of Depressive Symptoms Among Mothers of Children with Newly Diagnosed Epilepsy: A Longitudinal 10-Year Study

A substantial proportion of mothers of children with epilepsy are at risk for depression, and this risk is stable over the long term.

January 17, 2019

FDA Approves First Generic Version of Sabril to Help Treat Seizures in Adults and Pediatric Patients with Epilepsy

"Prioritizing the approval of generic drugs to compete with medicines that face little or no competition is a key part of our efforts to support access and reduce drug costs to patients," said FDA Commissioner Scott Gottlieb, MD.

January 17, 2019

Noninvasive Tests Help ID Seizure Site in Children with Focal Epilepsy

Naming tasks, which have helped to localize and lateralize a seizure onset region for surgery of focal epilepsy in adults, could now be as useful in children, with the recently reported success of a novel, age-specific assessment.

January 16, 2019

New Review Study Supports Ability of Epidiolex to Reduce Seizure Frequency in Dravet, Lennox-Gastaut Patients

Researchers in this study reviewed the main findings of these trials regarding the safety, efficacy, and tolerability of Epidiolex for the treatment of children with Dravet and Lennox-Gastaut syndromes.

January 15, 2019

Epilepsy Research Findings: January 2019

A round-up of the top epilepsy research news from the past month.

January 13, 2019

Central Nervous System Lymphatic Unit, Immunity and Epilepsy: Is There a Link?

Disruption of fluid drain rules related to the central nervous system may promote or sustain central nervous system disease, conceivably applicable to epilepsy where extracellular accumulation of macromolecules and metabolic by?products occur at the interstitial and perivascular spaces.

January 11, 2019

Researchers ID Factors Predictive of Naming Decline After Epilepsy Surgery

Paper- and online-based externally validated nomograms are effective in predicting naming decline after temporal lobe surgery in patients with epilepsy.

January 11, 2019

Poor Mental Health Support for Children in Epilepsy Clinics, National Audit in England and Wales Shows

Almost 9 in 10 Health Boards and Trusts in England and Wales do not enable mental health provision within epilepsy clinics.

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January 11, 2019

Heart Rate, Movement Detect Nocturnal Seizures in Epilepsy

Measurement of heart rate and movement using a multimodal bracelet sensor may be effective for detecting nocturnal seizures of varying types in patients with epilepsy.

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