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June 4, 2020

Trends in Hospitalization and Readmission for Pediatric Epilepsy and Underutilization of Epilepsy Surgery in the United States

This study provides novel insights into the current healthcare utilization for epilepsy and epilepsy surgery.

June 4, 2020

Healthcare Utilization and Associated Costs Following Initiation of Perampanel (Fycompa®) in Patients with Epilepsy

This study concludes that treatment with perampanel is associated with reduced epilepsy-related inpatient admissions and accident and emergency contacts.

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June 4, 2020

Long-Term Outcomes of Ketogenic Diet in Patients with Tuberous Sclerosis Complex-Derived Epilepsy

The ketogenic diet appears to be an effective therapeutic modality for intractable pediatric epilepsy in TSC, but it did not exhibit guaranteed efficacy over a long-term period, this study concludes.

June 4, 2020

Study Shows that Birth Defects Attributed to Valproate (Depakote®) Do Not Involve a Genetic Component

This study suggests that the genetic underpinnings of epilepsy do not contribute markedly to VPA-induced birth defects.

June 2, 2020

The Self-Stigma of Patients with Epilepsy in Japan: A Qualitative Approach

This study aims to investigate the quality and degree of cognition regarding self-stigma and to examine coping strategies in patients with epilepsy living in the community.

June 2, 2020

Influence of Stiripentol (Diacomit®) on Perampanel (Fyncompa®) Serum Levels

Researchers conclude that dose adjustments of stiripentol and perampanel when administered together, should be done carefully to avoid side effects or even severe intoxication.

June 2, 2020

A proposed Guideline for Vagus Nerve Stimulator Handling in Palliative Care and After Death

Researchers reviewed relevant literature to create a proposed guideline for management of patients with VNS in palliative care and after death.

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June 2, 2020

Post-Ictal Accelerometer Silence as a Marker of Post-Ictal Immobility

Researchers highlight a novel application of wearables as a way of recording post?ictal manifestations associated with an increased risk of SUDEP.

May 28, 2020

Study Shows that Cannabidiol (Epidiolex®) has Antiseizure Activity Independent of Its Interactions with Clobazam (Onfi®)

Thus study suggests a greater antiseizure effects and a greater burden of adverse effects, are observed when CBD is combined with CLB.

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May 28, 2020

Use of Ketogenic Diet Therapy in Infants with Epilepsy: A Review of the Scientific Literature

Analyses of uncontrolled studies estimate 59% of infants achieved at least 50% seizure reduction and 33% of infants achieved seizure freedom.

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May 27, 2020

CURE Discovery: Inhibition of an Important Brain Enzyme Attenuates the Development of Epilepsy

An adenosine kinase inhibitor may protect the brain from developing epilepsy by increasing adenosine levels, according to this CURE-funded work.

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May 26, 2020

Genetic Epilepsies and COVID-19 Pandemic: Lessons from the Caregiver Perspective

This study evaluates the impact of the pandemic on patients with genetic DEEs and their caregivers in Spain, one of the current hotspots of the pandemic.

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