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November 25, 2020

Advances in the Surgical Management of Epilepsy: Drug-Resistant Focal Epilepsy in the Adult Patient

Pharmacoresistant seizures occur in nearly one-third of people with epilepsy. Medial temporal lobe and lesional epilepsy are the most favorable surgically remediable epileptic syndromes...Read More

November 25, 2020

Affordability, availability and tolerability of anti-seizure medications are better predictors of adherence than beliefs: Changing paradigms from a low resource setting

Anti-seizure medication (ASM) non-adherence contributes to treatment gap and increases mortality and morbidity associated with epilepsy. Beliefs about medications are considered better predictors of ASM non-adherence than clinico-demographic factors. We aimed to look into ASM non-adherence rates among adults with epilepsy (AWE), identify the contributing barriers and determine whether medication beliefs were more powerful predictors than clinico-demographic factors.

November 25, 2020

Cognitive decline in older adults with epilepsy: The Cardiovascular Health Study

Cognitive decline is a major concern for older adults with epilepsy. Whether and how much faster older adults with epilepsy experience cognitive decline beyond expected age?related cognitive change remain unclear. We sought to estimate and compare rates of cognitive decline in older adults with and without epilepsy.

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November 25, 2020

Read the Latest CURE Epilepsy Report

Researching to CURE Epilepsy is our twice-yearly impact report. In it, you'll learn how we're making an impact by funding innovative research. Learn More.

November 23, 2020

Testing the ‘seizure scaffold’: What can experimental simulation tell us about functional seizures (seizures that resemble epileptic seizures but are not)?

It has been suggested for over 100 years that patterns of neurological symptoms and signs in functional neurological disorders may be shaped at a neural level by underlying ideas or preconceptions how neurological symptoms present. This study used experimental simulation to probe ideas about seizures in healthy volunteers, with a view to compare with features commonly observed in functional and epileptic seizure disorders.

November 23, 2020

Effects of valproate (Depakote), lamotrigine (Lamictal), and levetiracetam (Keppra) monotherapy on bone health in newly diagnosed adult patients with epilepsy

The aim of this study was to evaluate the effects of valproate (VPA), lamotrigine (LTG), and levetiracetam (LEV) on bone turnover and bone mineral density (BMD) in newly diagnosed adult patients with epilepsy...Read More

November 23, 2020

Proposal to Optimize Evaluation and Treatment of Febrile Infection?Related Epilepsy Syndrome (FIRES): A Report from FIRES Workshop

Febrile infection?related epilepsy syndrome (FIRES) is a rare catastrophic epileptic encephalopathy that presents suddenly in otherwise normal children and young adults causing significant neurological disability, chronic epilepsy and high rates of mortality...Read More

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November 23, 2020

Announcing the CURE Epilepsy Grantees!

These grants are awarded for novel research projects that address finding cures for epilepsy and address the goal of “no seizures, no side-effects.”

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November 23, 2020

Announcing our 2021 Grant Timeline!

These grants are awarded for novel research projects that address finding cures for epilepsy and address the goal of “no seizures, no side-effects.”

November 20, 2020

Preventive treatment positively alters ‘natural history of severe infantile epilepsy’

Preventive treatment with vigabatrin effectively altered the natural history of seizures among infants with tuberous sclerosis complex, decreasing the risk for and severity of epilepsy, according to results published in Annals of Neurology.

November 19, 2020

Approved: “WHO Global Actions on Epilepsy and Other Neurological Disorders”

ILAE is pleased to announce that on 12th November 2020 during the 73rd World Health Assembly, Member States unanimously approved a Resolution to develop a 10-year Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders.

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November 19, 2020

CURE Epilepsy Infantile Spasms Initiative: Using Team Science to Discover Novel Targets

Launched in 2013, CURE Epilepsy’s IS Initiative was an innovative interdisciplinary program designed to advance findings that could lead to better treatments for IS. It brought together eight research groups from different institutions who functioned as a united team, collaborating and sharing data to accelerate understanding of IS in an effective and efficient fashion...Read More

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