Dravet Syndrome, Treatment
A potential new gene therapy for Dravet syndrome increases survival and prevents seizures, according to initial tests in mice.
Mechanisms, Treatment Resistant/Refractory
In a large cohort of children with drug-resistant epilepsy, researchers showed that "fast ripples" are the best biomarkers to predict surgical outcomes, but they can be seen in only 43% of patients.
Genetics, Treatment Resistant/Refractory
Certain common genetic changes might make some people with focal epilepsy less responsive to seizure medications, according to a recent study conducted by CURE Epilepsy grantee Professor Sanjay Sisodiya of UCL Queen Square Institute of Neurology.
Genetics, Rare Epilepsies
The study found that patients with SCN8A-related disorders had more than 10-fold risk for developing bilateral tonic-clinic seizures as early as one year of age.
Dravet Syndrome
Recent research has identified defects related to metabolism in children with Dravet syndrome.
Tech/AI, Treatment, Treatment Resistant/Refractory
Researchers have developed an innovative deep brain stimulation (DBS) platform that can reduce seizures and also improve memory and sleep - two common challenges for people with epilepsy.
SUDEP
The largest pediatric case series on sudden unexpected death in epilepsy (SUDEP) to date was undertaken by Dr. Elizabeth Donner and colleagues to identify clinical factors that may be associated with SUDEP in childhood.
Treatment
A drug typically prescribed for arthritis halts brain-damaging seizures in mice with epilepsy, according to researchers in the lab of Avtar Roopra, PhD at the University of Wisconsin–Madison.
Tech/AI
Researchers have developed an artificial intelligence (AI) tool that can detect two-thirds of epilepsy brain lesions doctors often miss.
