The assay of saliva samples provides a valuable alternative to the use of blood samples for therapeutic drug monitoring (TDM), at least for certain categories of patients.
Psychoeducational interventions appear to have had positive results in Argentinian patients with PNES.
According to available literature, the global clinic-based lifetime prevalence of epilepsy in individuals with Down syndrome ranged from 1.6% to 23.1%, with epileptic spasms representing 6.7% to 66.7% of these cases.
This is the first study to provide objective evidence for a considerable negative effect of ZNS treatment on executive function, according to study authors.
The team demonstrated that both mutations lead to a significant gain in channel activity, and they observed a higher sensitivity to stimulation by an endogenous neurosteroid and heat.
Older US veterans who developed unprovoked seizures of unknown cause had double the risk of developing dementia over several years of follow-up.
Independent of current depression, use of pregabalin (Lyrica®) in the younger group and frequent seizures in the older group were associated with a risk of suicide.
In this month's Epilepsy Research News round-up, we feature stories discoveries on PNES, wearable devices and SUDEP risk, withdrawing from AEDs, and a link between autism and epilepsy.
This study suggests that, in older vulnerable patients with a cognitive disorder, careful consideration of AED initiation and close adverse events monitoring are needed.
