Pediatric Epilepsy
Absence epilepsy can be triggered by impaired communication between two brain regions: the cortex and the striatum.
Interictal dysphoric disorder (IDD) occurs in high frequency in people with epilepsy (PWE) with a substantial overlap of IDD with depressive and anxiety disorders.
Pediatric Epilepsy
Children with convulsive status epilepticus who undertook formal testing were shown to have significantly lower full-scale intelligence quotients and global memory scores from controls.
A retrospective, cross-sectional study has found that both BDNF and COMT may be associated with the pathophysiology of psychiatric comorbidities in patients with epilepsy.
This study shows the potential beneficial effect of vagus nerve stimulation in the treatment of patients with pharmacoresistant epilepsy and a comorbidity of symptoms of depression.
In people with epilepsy, the lifetime prevalence of suicidal ideation is twice that of people without epilepsy and those with epilepsy are 3 times more likely to attempt suicide than people without epilepsy.
New evidence suggests responsive neurostimulation can remodel the brain to be less susceptible to seizures.
Researchers are studying whether neural stem cell transplantation can reduce this abnormal adult neurogenesis in mice that have temporal lobe epilepsy.
The efficacy and the tolerability of lacosamide as monotherapy was favorable even at low doses in older patients and comparable with levetiracetam with a high rate of long-term seizure freedom.
