Temporal Lobe Epilepsy, Treatment Resistant/Refractory
A recent study finds that a small posterior part of the hippocampus may play a role in causing seizures, specifically in individuals who do not respond to anti-seizure medications or tissue ablation in the hippocampus.
Acquired Epilepsies, Adult-onset
A class of blood pressure medications, called angiotensin receptor blockers (ARBs), appear to help lower seniors’ risk of developing epilepsy, a new study finds.
Mechanisms
The findings suggest a promising target for developing treatments for epilepsy and preventing the downstream effects of seizures.
Treatment
Although 80% of people with epilepsy live in low- and middle-income countries (LMICs), most epilepsy research originates in high-income regions.
Dravet Syndrome, Rare Epilepsies
The improvements in skills like communication, behavior, socialization, and movement distinguish this approach from anything seen to date and mark the entry into a new era in the treatment of Dravet syndrome.
Sleep
The link between epilepsy and the breathing disorders of sleep apnea was strong. "People whose oxygen saturation fell below 80% during sleep, a condition known as nocturnal hypoxia, were three times more likely to develop late-onset epilepsy compared to those who did not have similarly low oxygen levels".
“With such a clear response, we have advanced our planning of the focal epilepsy efficacy study for PRAX-628, expected to begin in the second half of 2024. We extend our thanks to the patients who participated in this PPR study,”
Genetics, Mechanisms, Rare Epilepsies
This study reveals that the presence of KCNQ2 G256W variants affects both molecular and cellular aspects of KCNQ channel activity, including their ion-carrying capacity, expression, and placement within cells.
Tech/AI
Featuring work from CURE Epilepsy Grantee Dr. Maxime O. Baud. Researchers have developed a new method for triggering and imaging seizures in epilepsy patients, offering physicians the ability to collect real-time data to tailor epilepsy surgery.
