Research Grants Awarded

CURE Epilepsy sees research as the key to finding cures for the epilepsies. Each year, CURE Epilepsy funds investigator-initiated grants supporting promising trends in the field and the potential for breakthroughs in a specified area.

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SUDEP Clinical Biomarker Team Science Award

Integrative AI-driven Analysis of Genetic, Cardiac, Neurophysiological, and Sleep-related Risk Factors for Personalized SUDEP Risk Prediction

Satya Sahoo, PhD / Case Western Reserve University

Using advanced artificial intelligence, this team aims to make advances that will facilitate the development of a personalized risk prediction tool that can estimate an individual’s SUDEP risk and clearly explain the reasons behind it.

SUDEP Clinical Biomarker Team Science Award

Understanding the Cardiac Basis of SUDEP in Alternating Hemiplegia of Childhood

Andrew Landstrom, MD, PhD / Children's Hospital of Philadelphia

This project will identify which children are at highest risk and which medications are safest, with the goal of preventing sudden death and providing families and guiding clinical care of patients.

SUDEP Clinical Biomarker Team Science Award

Identifying Clinical Biomarkers and Developing Multimodal Risk Prediction Tools for SUDEP Prevention

Shobi Sivathamboo, PhD / Monash University

By analyzing patterns in heart rhythm, breathing, brain activity, arousal, and sleep, this project aims to uncover measurable warning signs of risk to inform prevention strategies.

Rare Epilepsy Partnership Award

Gene Therapy for Seizures in a Mouse Model of a Pathogenic GRIK2 Variant

Geoffrey Swanson, PhD / Northwestern University

Dr. Swanson’s team will test whether reducing the activity of the overactive kainate receptor, using a gene therapy approach, can improve seizures and other behaviors in a new mouse model that carries the same genetic change found in people.

Rare Epilepsy Partnership Award

Defining Epilepsy and Therapeutic Targets in CTNNB1 Syndrome: An Integrated Preclinical-Clinical Platform

Damon Page, PhD, with Emily Neuhaus, PhD, and Sara Webb, PhD / Seattle Children’s Hospital

In this project, Dr. Page and his team will study seizures in a CTNNB1 mouse model using continuous video‑EEG recording and tests that measure the level of stimulation needed to trigger a seizure.

Rare Epilepsy Partnership Award

Establishing KCNQ2 p.G281R Mouse as a Preclinical Model for Therapeutic Discovery

Anil Akturk, PhD / The Jackson Laboratory

Dr. Akturk’s team has developed a new “humanized” mouse model that carries a human KCNQ2-DEE variant called p.G281R. Dr. Akturk’s team proposes to characterize seizures, cognition, and brain pathology in this model.