Traumatic Brain Injury Awards
Adi Mizrahi, PhD / The Hebrew University of Jerusalem, Israel
In this three-year project, Dr. Mizrahi will study the changes within the brain that underlie the development of post-traumatic epilepsy in mice.
Traumatic Brain Injury Awards
Philip Schwartzkroin, PhD / University of California, Davis, CA
In this two-year project, Dr. Schwartzkroin will study potential protective therapies in a rat model of traumatic brain injury.
Multidisciplinary Awards, Funded by the Christopher Donalty and Kyle Coggins
Dmytro Isaev, PhD / Bogomoletz Institute of Physiology, Kiev, Ukraine
In this one-year study, Drs. Holmes and Isaev will build upon these exciting preliminary results and determine whether modification of sialic acid reduces seizures in a mouse model of epilepsy and prevents the onset of epilepsy following brain injury.
Traumatic Brain Injury Awards
Detlev Boison, PhD / R.S. Dow Neurobiology Labs
Dr. Boison will examine how failures in the adenosine system develop as a consequence of brain injury, how these failures contribute to the development of spontaneous recurrent seizures, and how the development of epilepsy can be prevented by transient application of adenosine-related drugs during a critical window of time after the injury.
Multidisciplinary Awards
Steven Rothman, MD / University of Minnesota Medical School/Washington University
The goal of their research is to terminate seizures using compounds activated by light without affecting the function of the rest of the brain.
Multidisciplinary Awards, Funded by the UCB Award
Audrey Yee, MD / University of Colorado, Boulder
Dr. Audrey Yee, an epilepsy researcher and clinical neurologist, and Dr. Amy Yee, a breast cancer and Wnt signaling researcher, will investigate new mechanisms and therapeutic strategies to treat epilepsy.
Jenny Hsieh, PhD / The University of Texas Southwestern Medical Center/The Nathan Kline Institute for Psychiatric Research
Drs. Hsieh and Scharfman will collaborate to block neurogenesis in an animal model of TLE to resolve this issue.
In Memory of Christopher Donalty and Kyle Coggins
Alicia M. Goldman, MD, PhD / Baylor College of Medicine, Houston, TX
Dr. Goldman’s research is focused on identifying mutations in ion channel genes found in both the heart and the brain that underlie both cardiac arrhythmias and seizures, and may ultimately lead to Sudden Unexpected Death in Epilepsy (SUDEP).
The 2009 Henry Lapham Memorial Award
Elizabeth Donner, MD / University of Toronto, Hospital for Sick Children
Using a network of collaborators across Canada, she will implement a registry that will collect data on every child in Canada with SUDEP.