Post-Traumatic Epilepsy Initiative
Pavel Klein, MD / Mid-Atlantic Epilepsy and Sleep Center, LLC
Dr. Pavel Klein and his team seek to address this problem by examining a group of “high-risk” patients with a greater chance of developing post-traumatic epilepsy.
CURE Epilepsy Award
Nicholas Varvel, PhD / Emory University
For their project, Dr. Varvel and his team are interested in using a small drug to block monocyte entry in mouse brains after SE.
Post-Traumatic Epilepsy Initiative
Dr. Jeffrey Loeb / University of Illinois, Chicago
By examining patients with subarachnoid hemorrhage and an animal model of subarachnoid hemorrhage, the Loeb team will use methods such as MRI and EEG to characterize the development of PTE with the aim of understanding and predicting who is at risk for developing this condition and identifying potential treatment strategies.
Infantile Spasms Initiative
John W. Swann, PhD / Baylor College of Medicine
This commentary discusses three aspects of IESS intended to raise fundamental clinical and mechanistic issues to afford greater understanding of the syndrome – nomenclature, EEG findings, and selected emerging animal models that might shed light on IESS pathophysiology and guide therapy development.
Innovator Award
Jozef Gecz, PhD / University of Adelaide
In this project, Dr. Gecz and his team will isolate cfDNA from patients’ blood in the hours after a seizure(s).
Taking Flight Award, Funded by the Ravichandran Foundation
Juliet Knowles, MD, PhD / Stanford University
Her current project will determine if seizures cause myelin abnormalities and if abnormal myelin contributes to the development of epilepsy and associated cognitive impairment.
Taking Flight Award
Lakshmi Subramanian, PhD / The Regents of the University of California at San Francisco
Taking Flight Award
Jennifer Gelinas, MD, PhD / Columbia University Medical Center
Dr. Gelinas and her team will leverage new technology to acquire high-resolution “maps” of neural networks in animals with progressive focal epilepsy.
Post-Traumatic Epilepsy Initiative
Harald Sontheimer, PhD / Virginia Tech
Dr. Harald Sontheimer and his team have identified the need for additional animal models of post-traumatic epilepsy, and plan to utilize both a new mouse model of post-traumatic epilepsy alongside an established model to investigate the ways in which traumatic brain injury leads to post-traumatic epilepsy.
