Post-Traumatic Epilepsy
Captain Jack Somers was familiar with operating in stealth mode, hidden from enemies. But unbeknownst to him, similarly covert changes were taking root in his brain after a particularly close grenade blast experienced in 2010 while serving overseas.
Genetics
These genes included some known FCD genes, as well as six new genes that could also contribute to FCD.
SUDEP
CURE Epilepsy has long been leading the charge in funding research on seizure-related biomarkers and is committed to advancing this research as it will have the potential to improve outcomes for people with epilepsy by identifying, for example, who may be at risk for epilepsy after a stroke to who may be at risk for epilepsy following a brain injury to who may not respond to antiseizure medications.
SUDEP
CURE Epilepsy has been a leader in driving awareness and research on SUDEP since 2004, when it started the first private research program to investigate SUDEP and its prevention.
Acquired Epilepsies
Studying brain activity to identify biological signals (biomarkers) may help predict who will develop epilepsy following a brain injury.
Rare Epilepsies
To better understand the clinical manifestations and treatment of EEM, CURE Epilepsy convened a panel of EEM expert neurologists and individuals with EEM lived experience to summarize existing knowledge, develop consensus about the diagnostic approach and clinical management of EEM and identify areas where further study is needed.
Acquired Epilepsies
Dr. Varvel’s team found that using a drug to reduce the invasion of monocytes from the blood into the brain minimized the harmful effects of status epilepticus, such as a loss in functional impairment and inflammation.
Post-Traumatic Epilepsy
The PTE Initiative has led to many scientific successes to date: PTE Initiative teams developed and characterized several different laboratory-based models of PTE, enhanced the understanding of the biological underpinnings of PTE, and identified potential risk factors and potential biomarkers for PTE.
Acquired Epilepsies
This work is instrumental not only to understand why and how the brain generates and sustains seizures, but also to discover biomarkers that could predict if someone will have seizures, or how they may respond to a drug.