Prevention of Epilepsy After Brain Injury Award, Funded by the CJM Foundation
Vijayalakshmi Santhakumar, PhD / New Jersey Medical School
Dr. Santhakumar’s research will focus on a class of innate immune receptors known to regulate neuronal growth and excitability and determine their contribution to hippocampal structural and functional changes after brain injury.
Taking Flight Award
Jeffery Tenney, MD, PhD / Cincinnati Children’s Hospital Medical Center
The goal of Dr. Tenney’s research is to use state-of-the-art neuroimaging to compare areas of seizure onset in children with medication responsive and non-responsive epilepsy.
Challenge Awards, Funded by the Rhode Island Award
Scott Baraban, PhD / University of California, San Francisco
Dr. Baraban seeks to shift current research in the epilepsy field in two ways.
Challenge Awards
Sacha D. Nelson, MD, PhD / Brandeis University
Dr. Nelson will explore the hypothesis that blocking normal activity causes a secondary change in interneurons, impairing cortical inhibition.
Prevention of Epilepsy After Brain Injury Award, Funded by the Brighter Future Award
Yogendra Raol, PhD / University of Colorado, Denver
Dr. Raol’s project will examine whether a potassium channel opener (flupirtine) can treat HI-induced neonatal seizures and alter long-term adverse neurological outcomes in an animal model of HI.
Challenge Awards, Funded by the Heldman Family/CURE Award
Robert Fujinami, PhD / University of Utah
We propose to test the hypothesis that virus infection activates the complement system in the brain that in turn increases inflammation which ultimately contributes to the development of seizures.
Multidisciplinary Awards, Funded by the Brighter Future Award
Steven Schiff, MD, PhD / Pennsylvania State University
Our translational approach focuses on fusing fundamental biology and clinical principles to help guide future human clinical trials.
Challenge Awards, Funded by the CJM Foundation
Peter Crino, MD, PhD / Temple University
If our data is correct, the future for patients with FMCD may include targeted therapy to cure HPV16 infection that could lead to truly new and successful treatment strategies with improved efficacy (“no seizures”) and diminished morbidity (“no side effects”).
Multidisciplinary Award, Funded by the Dravet Syndrome Foundation
Jingqiong “Katty” Kang, MD, PhD / Vanderbilt University
We propose to use photoluminescent nanoparticles called quantum dots to perform 3D super-resolution tracking of the dynamic behaviors of this protein family in live neurons in the mutation-carrying mice.
