Multidisciplinary Awards
Carl Faingold, PhD / Southern Illinois University School of Medicine
This collaborative project between Dr. Faingold, an epilepsy researcher and Dr. Utsehev-Gaard, a basic neuroscientist, will determine if novel drugs acting on serotonin will block SUDEP in DBA/2 mice with lower doses and fewer side effects.
Multidisciplinary Awards, Funded by the Central New York Award, in Memory of Christopher Donalty and Kyle Coggins
Anne Anderson, MD / Baylor College of Medicine, Houston, TX
The studies will be performed as an interdisciplinary collaboration between Dr. Anderson, an epilepsy researcher, and Dr. Vatta, a cardiovascular researcher with expertise in myocardial remodeling and channelopathies.
Traumatic Brain Injury Grantees
Raimondo D'Ambrosio, PhD / University of Washington, Seattle, WA
This project aims to achieve two goals by employing our recently developed model of posttraumatic epilepsy, in which chronic recurrent spontaneous partial seizures reliably appear in the rat following a realistic insult (FPI) presenting mechanical features very similar to human closed head injury.
Traumatic Brain Injury Grantees
Scott Thompson, PhD / University of Maryland School of Medicine, Baltimore, MD
Using laboratory rats, the team will be testing the mechanisms that the cells use to compensate for the lack of activity and also test a class of medicines that may counteract those changes.
Traumatic Brain Injury Grantees
Asla Pitkänen, MD, PhD, DSci / University of Kuopio, Finland
This projects aims at developing new, clinically relevant animal models that can be used to investigate molecular mechanisms of epileptogenesis after TBI and to test novel candidate treatments for prevention of post-traumatic epilepsy (PTE).
Traumatic Brain Injury Grantees
Maiken Nedergaard, MD, PhD / University of Rochester, Rochester, NY
This project offers a new conceptual and operational approach to understanding the cellular basis of seizure disorders.
Traumatic Brain Injury Grantees
James O. McNamara, MD / Duke University Medical Center, Durham, NC
The goal of this work is to develop a closed head injury model of PTE in a mouse strain that is amenable to genetic manipulation.
Traumatic Brain Injury Grantees
Matthew Smyth, MD, / Washington University, St. Louis, MO/University of Washington, Seattle, WA
The experiments planned include the administration of direct focal cooling at the FPI site after the development of post-traumatic chronic seizures in order to evaluate the anti-seizure effect of focal cortical cooling.
Multidisciplinary Awards, Funded by the Northwestern Dance Marathon Award
Julie Blendy, PhD / University of Pennsylvania Children’s Hospital of Philadelphia
Dr. Porter, an epilepsy researcher, and Julie Blendy, a pharmacologist will examine whether one of the master regulators of neuronal survival and gene expression, CREB, is necessary for animals to develop epilepsy after brain injury.
