CURE Epilepsy Award, Funded by the Hope Foundation
Brenda E. Porter, MD, PhD / Children’s Hospital of Philadelphia
This study tries to understand which molecules in the cortical dysplasia neurons are different and how these differences cause epilepsy.
The Maggie Loeffel Award
Edward Perez-Reyes, PhD / University of Virginia
Dr. Perez-Reyes strives to develop a T-type channel blocker as a novel anti-epileptic medication, which can be used in significantly lower doses to substantially reduce debilitating treatment side effects for these children.
CURE Award, Funded by the Graham Goddard Young Investigator Award
Alexander Rotenberg, MD, PhD / Boston Chidren’s Hospital, Brookline, MA
CURE Award
Tracy Butler, MD / Weill Medical College of Cornell University, New York, NY
This project will use Positron Emission Tomography (PET) scanning to examine inflammation in the brains of patients with uncontrolled focal epilepsy.
CURE Award, Funded by the Christopher Donalty Interdisciplinary Award
Jenna L. Rickus, PhD, / Purdue University, West Lafayette, IN
The goal of this project, which melds biology and engineering, is to develop a novel, cell-based neural prosthetic to electrically detect a seizure before it occurs and respond by stimulating transplanted cells to rapidly release GABA, thereby preventing the seizure.
CURE Award, Funded by the Maggie Loeffel Award
Walter M. St. John, PhD / Dartmouth Medical School, Lebanon, NH
This investigator will categorize changes in breathing during seizures and describe how these changes might be responsible for SUDEP.
CURE Award
Vittorio Gallo, PhD / Children’s National Medical Center/George Washington University, Washington DC
This study will investigate the transfer of progenitor cells to replace inhibitory neurons lost in patients with temporal lobe epilepsy as a means of re-establishing normal function.
CURE Award, Funded by the Rhode Island Award
Nikolaus J. Sucher, MD / Children’s Hospital & Harvard Medical School, Boston, MA
This study will investigate the molecular details of the interaction and function of selected proteins, which may suggest novel targets for the treatment of TSC and epilepsy.
CURE Award, Funded by the Falk Medical Research Trust
Heidrum Potschka, DVM / Ludwig-Maximilians-University, Munich, Germany
The aim of Dr. Potschka’s project is to test whether resistance can be overcome by downregulating the expression of the major multidrug transporter P-glycoprotein by RNA interference (RNAi).
