CURE Award, Funded by the Graham Goddard Young Investigator Award
Transcranial Magnetic Stimulation: Anticonvulsant And Antiepileptic Properties
Alexander Rotenberg, MD, PhD
Boston Chidren’s Hospital, Brookline, MA
Transcranial magnetic stimulation (TMS) can potentially be used to interrupt ongoing seizure activity, prevent epilepsy after an event such as status epilepticus, and increase seizure-free periods. Yet, TMS is in the early stages of development, and the field would benefit from the use of animal models to evaluate whether seizures can be shortened with this technique and whether TMS can protect against the development of chronic epilepsy. This study will examine the utility of TMS in a rat model of epilepsy. The results will guide the use of TMS in patients with epilepsy and the prevention of epilepsy in those patients at risk.