Rare Epilepsy Partnership Award
Vincent Navarro, MD, PhD / Sorbonne University, Paris Brain Institute
This study aims to explore whether there are clinical signs, brain imaging markers, or certain molecules in the blood and cerebrospinal fluid that can help us predict who might develop epilepsy after NORSE.
Rare Epilepsy Partnership Award
Michael Talkowski, PhD / Massachusetts General Hospital
Dr. Talkowski and his team propose to create a complete map of structural genetic changes, DNA methylation patterns, and gene expression changes in Ring14 syndrome.
Rare Epilepsy Partnership Award
Hing Lee, PhD / Boston Children's Hospital
In this study, Dr. Lee will test whether gene replacement therapy, a treatment aimed at delivering normal copies of the SLC6A1 gene to the brain, can improve symptoms in mice lacking the SLC6A1 gene.
CURE Epilepsy Award
Sanjay Sisodiya, PhD, FRCP / University College London
For this project, the team will build on their preliminary findings by comparing genetic information from people who sadly succumbed to SUDEP with that from a matched group of living people with epilepsy.
Taking Flight Award
Vishnu Cuddapah, MD, PhD / The Children’s Hospital of Philadelphia
Dr. Cuddapah will use a fruit fly (Drosophila) model to identify mechanisms that tie sleep disruption to increased seizure severity.
CURE Epilepsy Award
Berge Minassian, MD / The University of Texas Southwestern Medical Center
Results from this project will lead to initial data on a possible treatment for a devastating form of epilepsy.
Taking Flight Award
Rachel June Smith, PhD / University of Alabama at Birmingham
Dr. Rachel June Smith will build computational models to virtually stimulate the brain and identify regions of hyperexcitability.
Taking Flight Award
Cathryn Cadwell MD, PhD / University of California, San Francisco
Dr. Cadwell will study single cells from surgically resected tissue from patients to better understand the molecular, anatomical, and electrophysiological changes that cause seizures in FCD.
CURE Epilepsy Award
Gemma Carvill, PhD / Northwestern University
Dr. Carvill’s team will determine if residual biological material on depth electrodes used during evaluation of patients for potential surgery can be used to study epilepsy.
