Taking Flight Award
Gaia Novarino, PhD / Institute of Science and Technology, Austria
We aim to employ human “mini brains” to compare the effect of a large number of genetic mutations and identify points of intersection between distinct forms of EIEEs.
Innovator Award, Funded by the Team S4 Award
Angelique Bordey, PhD / Yale University
If exosomes released from “epileptic” neurons do alter the function of healthy neurons, this would open up an entirely new field of epilepsy research.
Pediatric Epilepsies Awards
Glenn King, PhD / The University of Queensland, Australia
We have identified compounds that enhance Nav1.1 function in order to control seizures, and we aim to develop these molecules as therapies.
Pediatric Epilepsies Awards, Funded by the Team S4 Award
Natalia De Marco Garcia, PhD / Cornell University
We will focus our studies in a subset of inhibitory neurons since our previous work indicates that these neurons are exquisitely sensitive to environmental stress in newborns.
Taking Flight Award
Darren Goffin, PhD / The University of York, United Kingdom
These studies will provide new insights into the pathogenesis of seizures in RTT and may aid in the development of new strategies for their control.
Prevention of Acquired Epilepsies Awards
Mouhsin Shafi, MD, PhD / Beth Israel Deaconess Medical Center
We will utilize a noninvasive brain stimulation technique, Transcranial Magnetic Stimulation (TMS), in combination with electroencephalography (EEG) to evaluate brain excitability, and thereby the risk of developing epilepsy, in patients with an acquired brain infection called Progressive Multifocal Leukoencephalopathy (PML).
Prevention of Acquired Epilepsies Awards
Karen Newell-Rogers, PhD / Texas A&M University System Health Science Center
The purpose of this proposal is to determine if we can prevent PTE by selectively targeting a damaging immune response after TBI.
SUDEP, Funded by the CURE & HOPE4SUDEP
Edward Glasscock, PhD / LSU Health Sciences Center in Shreveport
The envisioned project has the potential to widen this field by applying bioengineering analytical principles to identify interactions and associations between biosignals that can be used to predict SUDEP risk.
SUDEP
Lori Isom, PhD / University of Michigan
We will test the hypothesis that genetic epilepsy patients who are at greater risk of SUDEP will exhibit a higher beating rate and higher levels of sodium current in their iPSC-cardiac heart cells compared to people who do not have epilepsy.
