Pediatric Epilepsy
The ERGENT program provides free-of-charge genetic testing to babies who have features suggestive of a genetically-caused epilepsy.
Genetics
Advances in the ‘omics’, genetic epilepsy models and deep-phenotyping techniques have revolutionary translational research potential that can bring precision medicine to the forefront of clinical practice in the coming decade.
The use of predictive AI models may ensure patients with predicted drug-resistant epilepsy receive specialist care with potentially more aggressive therapeutic interventions from diagnosis, to help reduce the serious sequelae of drug-resistant epilepsy.
A round-up of top epilepsy research news from the past month.
Epilepsy and Alzheimer's Disease appear to be associated. People with Alzheimer’s disease have a high risk of developing seizures—more than 80 times the risk of people who don’t have Alzheimer’s.
Outcomes suggest an association of hypertension, diabetes, smoking, APOE ?4 allele number, activity level, and alcohol use with late-onset epilepsy.
Selective placement of stimulation electrodes along the corpus callosum could be used as a patient?specific treatment for cortical epilepsies.
In this cohort, the overall mortality of first?time nonhypoxic status epilepticus was >50%. Mortality of status epilepticus after discharge was substantially higher than in?house mortality and stabilized after 2 years.
Adjunctive perampanel demonstrated a favorable safety profile and long-term tolerability in Japanese patients with refractory partial-onset seizures for ?316 weeks.
