Pediatric Epilepsy
Only about one-quarter of children with absence epilepsy in this study became seizure free with levetiracetam. Lack of seizure control requiring continued dose escalation should prompt early consideration of a therapeutic medication transition.
Genetics
Scientists at the UNC School of Medicine have found evidence that genetic therapy may prevent the enhanced seizure susceptibility.
Pediatric Epilepsy
Organoids promise hope of a cure for illnesses ranging from childhood epilepsy to Alzheimer’s.
Pediatric Epilepsy
The ERGENT program provides free-of-charge genetic testing to babies who have features suggestive of a genetically-caused epilepsy.
Genetics
Advances in the ‘omics’, genetic epilepsy models and deep-phenotyping techniques have revolutionary translational research potential that can bring precision medicine to the forefront of clinical practice in the coming decade.
The use of predictive AI models may ensure patients with predicted drug-resistant epilepsy receive specialist care with potentially more aggressive therapeutic interventions from diagnosis, to help reduce the serious sequelae of drug-resistant epilepsy.
A round-up of top epilepsy research news from the past month.
Epilepsy and Alzheimer's Disease appear to be associated. People with Alzheimer’s disease have a high risk of developing seizures—more than 80 times the risk of people who don’t have Alzheimer’s.
Outcomes suggest an association of hypertension, diabetes, smoking, APOE ?4 allele number, activity level, and alcohol use with late-onset epilepsy.
