Mechanisms
“These findings not only deepen our understanding of how seizures originate but are expected to have a wider impact on several neurological diseases."
Adult-onset
As a large population of patients with epilepsy ages, risk of hyponatremia has become an important clinical concern, in which monitoring of serum sodium levels when receiving antiseizure medications or antipsychotics (ASMs) may help identify and minimize the risk of hyponatremia in patients with epilepsy.
Treatment
The current review presenting a list of plants with antiepileptic effects aims to pave the way for finding alternative drugs with fewer side effects for scientists.
Treatment
Intra-operative seizures (IOS) can occur during awake craniotomies (AC) for brain tumors. They can potentially result in an increased risk of morbidity; however, literature is scarce on IOS, its risk factors, and predictors.
Genetics, Mechanisms, Treatment
Our understanding of the genetics and pathophysiological mechanisms underlying HCN1 epilepsy has progressed significantly and is already influencing therapy.
Rigorously designed biomarker studies with methods acceptable to the regulatory bodies should be conducted.
New epilepsy research on epilepsy, seizures, post-traumatic epilepsy, and antiseizure medications in this issue of Epilepsy Research News.
Mechanisms
“To our knowledge, this is the first study to implicate the cerebellum in a pathway that alters the activity of a specific group of neurons in an area called the ventral posteromedial nucleus (VPM) in the thalamus to cause generalized seizures."
Treatment, Treatment Resistant/Refractory
We present a quantitative measure of seizure severity that includes EEG and clinical features, validated on gold standard in-patient recordings.
