Treatment
Intra-operative seizures (IOS) can occur during awake craniotomies (AC) for brain tumors. They can potentially result in an increased risk of morbidity; however, literature is scarce on IOS, its risk factors, and predictors.
Genetics, Mechanisms, Treatment
Our understanding of the genetics and pathophysiological mechanisms underlying HCN1 epilepsy has progressed significantly and is already influencing therapy.
Rigorously designed biomarker studies with methods acceptable to the regulatory bodies should be conducted.
New epilepsy research on epilepsy, seizures, post-traumatic epilepsy, and antiseizure medications in this issue of Epilepsy Research News.
Mechanisms
“To our knowledge, this is the first study to implicate the cerebellum in a pathway that alters the activity of a specific group of neurons in an area called the ventral posteromedial nucleus (VPM) in the thalamus to cause generalized seizures."
Treatment, Treatment Resistant/Refractory
We present a quantitative measure of seizure severity that includes EEG and clinical features, validated on gold standard in-patient recordings.
Acquired Epilepsies
Patients with psychogenic nonepileptic seizures (PNES) experienced seizures significantly earlier than patients with epileptic seizures (ES), suggesting that seizure latency may help physicians differentiate between the seizure types.
Watch our PSA that's aired on ESPN, save the date for the virtual UNITE to CURE Epilepsy event, and more in this CURE Epilepsy Update!
Adult-onset
Longer duration of epilepsy was associated with the lower practice of physical activity, but physical activity was associated with better performance in aspects of cognition.