anti-seizure medication withdrawal at ?16?years of age and a diagnosis other than juvenile absence epilepsy may be independent risk factors for seizure recurrence after drug withdrawal in adolescent patients.
We demonstrate that assessment of TBI-induced hippocampal deformation by clinically translatable MRI methodologies detects subjects with prior TBI as well as those at high-risk of PTE, paving the way towards subject stratification for antiepileptogenesis studies.
The present study by CURE Epilepsy grantee Dr. Scott Baraban extends this approach to a preclinical zebrafish model representing STXBP1-related disorders, and suggests that future clinical studies may be warranted.
New evidence from a zebrafish model of epilepsy may help resolve a debate into how seizures originate, according to Weill Cornell Medicine and NewYork-Presbyterian investigators. The findings may also be useful in the discovery and development of future epilepsy drugs.
Evidence showing that the immature brain is vulnerable to seizure-induced damage has been accumulating for decades. Clinical data have always suggested that some early life seizures are associated with negative sequellae, but clinical observations are frequently obscured by multiple uncontrolled contributing factors and can rarely establish causality.
Patients with dementia have higher risk of epilepsy. However, it remains not comprehensively evaluated if late-onset epilepsy (LOE) is associated with higher risk of dementia.
It started in a high school physics class in Duluth, Georgia, when Ashley Galanti was given the assignment to create something to help people with diseases. Both her mother and brother have epilepsy, so she designed a wearable case holding a mouth guard used to protect people during seizures.
CBD
In this month's Epilepsy Research News we highlight inaccurately labeled CBD products, the first FDA-approved drug, Ztalmy®, to treat seizures for CDLK5 deficiency disorder (CDD), and more.
While the brain accounts for just 2% of human body mass, it expends almost 20% of the body's daily energy production. In order to maintain this high energy demand brain cells are nourished by an intricate network of capillaries that forms the so-called blood-brain barrier (BBB). Such is the extent of these capillaries, we estimate that every brain cell is essentially nourished by its own capillary.
