Pediatric Epilepsy
A web-based application could help doctors diagnose epilepsy in children following an initial paroxysmal event with little information to differentiate epilepsy from other possibilities.
Failure to correct medication nonadherence resulted in an increase in daily seizure burden in rats, even following dose escalation.
Total direct costs of Dravet Syndrome patients (excluding drugs) are driven by non-seizure-related healthcare use and high seizure burden is associated with higher healthcare costs.
This 50-year, long-term follow-up demonstrates a better outcome for seizure freedom compared to our follow-up after 12 years and to previous reports.
Sleep disturbances are associated with impaired memory and executive function in patients with refractory focal epilepsy and to a lesser extent, among those with medically controlled epilepsy.
This study aimed to determine if differential long-term neurodevelopmental effects exist across four commonly used AEDs (carbamazepine, lamotrigine, phenytoin, and valproate).
Genetics
Study may confirm a convergence in the genetics of common and rare epilepsies associated with ultra-rare coding variation and highlights a ubiquitous role for GABAergic inhibition in epilepsy etiology.
A new animal model could improve understanding of post-traumatic epilepsy.
Magnetic resonance thermography-guided stereotactic laser ablation was found to be an effective alternative to open surgery for epileptogenic cerebral cavernous malformations.
