Ketogenic Diet, Pediatric Epilepsy
Children achieving drug-free diet therapy were more likely to be younger, have fewer antiseizure drugs at ketogenic diet onset, have Glut1 deficiency or epilepsy with myoclonic-atonic seizures, but were less likely to have Lennox-Gastaut syndrome or a gastrostomy tube.
Patients with epilepsy who respond to eslicarbazepine acetate (ESL), have a seizure frequency reduction (SFR) of greater than or equal to 75%, and are at the lower SFR threshold of greater than or equal to 50% have higher health-related quality of life (QoL) compared with nonresponders to ESL.
Study designs allowing for long-term comparative observations would be of great value, but are hindered by the inherent nature of a long-term [surgical] control group and the bias associated with open-label trials.
Based on aggregated clinical data analytics, the project will provide insights into disease progression and responses to treatment.
This webinar discusses how epilepsy patients, their families, and pediatric neurologists can develop a plan to prepare for the transition of care.
Researchers find that perampanel increases assessment scores indicative of aggression as well as depression.
A Grayling-area man is the first in Michigan with a complete Deep Brain Stimulation (DBS) system surgically implanted for the treatment of epilepsy
Pediatric Epilepsy
NeuroCycle Therapeutics was awarded a $0.5M Small Business Innovation Research grant from the NINDS to evaluate its advanced subtype-selective GABAA receptor modulators in models of Dravet Syndrome.
The 5-year grants support different studies, both focused on understanding the pathophysiology of ion channel-related disorders, including epilepsy, in search of viable therapies.
