A retrospective, cross-sectional study has found that both BDNF and COMT may be associated with the pathophysiology of psychiatric comorbidities in patients with epilepsy.
This study shows the potential beneficial effect of vagus nerve stimulation in the treatment of patients with pharmacoresistant epilepsy and a comorbidity of symptoms of depression.
In people with epilepsy, the lifetime prevalence of suicidal ideation is twice that of people without epilepsy and those with epilepsy are 3 times more likely to attempt suicide than people without epilepsy.
New evidence suggests responsive neurostimulation can remodel the brain to be less susceptible to seizures.
Researchers are studying whether neural stem cell transplantation can reduce this abnormal adult neurogenesis in mice that have temporal lobe epilepsy.
The efficacy and the tolerability of lacosamide as monotherapy was favorable even at low doses in older patients and comparable with levetiracetam with a high rate of long-term seizure freedom.
his study suggests that a shorter duration yet deeper therapeutic coma as treatment for refractory status epilepticus may be more effective and safer than the currently recommended duration of 24?48 hours.
This study found a rate of 13.6% for late seizure recurrence after weaning from at least one antiseizure drug in patients with new onset status epilepticus.
Initial findings suggest that valproate can affect the function of the human placenta during early pregnancy.