Researchers propose ketamine be started early in the course of status epilepticus as a neuroprotectant and that it be continued until epileptic discharges are eliminated.
Potential major or moderate interactions between AED(s) and other drugs are noted in 30.1% of patients exposed to at least one medication other than AED (12.1% of the entire cohort).
Pediatric Epilepsy
The aim of this review is to provide a neuropsychological framework to enhance and support clinical decision-making in the pre-surgical evaluation of children with focal-onset epilepsy.
Neuroelectrics Corporation presented positive results from its clinical trial treating patients with drug resistant epilepsy with Starstim™, a device that uses mild electric currents applied on the scalp to calm abnormal activity of the brain.
Scientists discovered the important role alpha2delta4 between the nerve cells, a puzzle piece that plays a decisive role in the development of epilepsies and is a possible starting point for therapies.
Genetics
A Global Epilepsy Whole Genome Study will sequence 1,000 patients diagnosed with epilepsy over the next nine months, further advancing the research and development of gene therapies for epilepsy.
SUDEP
Low interictal hypercapnic ventilatory response may increase the risk of severe respiratory depression and SUDEP after generalized convulsive seizures and warrants further study.
The primary outcome measure was the 46-item Attitudes and Beliefs about Living with Epilepsy (ABLE) scale, scored on a five-point Likert scale.
This paper reviews the largely unexplored role of neuroendocrine factors in epilepsy-related depression, focusing on Growth Hormone.
