Although antiepileptic drugs are used to treat epilepsy resulting from a tapeworm or tuberculosis, the duration of this treatment is still debated.
Neuroscientists describe how the common Toxoplasma gondii parasite prompts the loss of inhibitory signaling in the brain by altering the behavior of nearby cells called microglia.
Implementation of patient self-management programs to improve seizure control may reduce epilepsy impact for Veterans and reduce Veterans Affairs (VA) healthcare utilization.
From live streams to kids' activities, there's plenty happening around the CURE community this month!
Pediatric Epilepsy
Researchers generated a KCNQ2?related epileptic encephalopathy mouse model to study the pathophysiology and perform preclinical research.
According to the authors, this study established a simple, practical, and evidence-based prediction score for predicting seizure freedom with antiepileptic drugs to aid in the clinical consultation and treatment decision for the newly diagnosed patients with MRI-negative epilepsy.
Here, the authors describe the preclinical basis for applying interneuron transplantation to human epilepsy, discuss its potential clinical applications, and consider the translational hurdles to its development as a surgical therapy.
Pediatric Epilepsy
Initial data suggest that soticlestat continues to be safe and well tolerated and appears to reduce seizure frequency in a majority of the individual patients.
During the COVID-19 pandemic, CURE remains laser-focused on funding critically-needed research to drive science closer to a cure for epilepsy.