A network of connections in the brain could be the key to improving frontal lobe epilepsy surgery.
occupational (work-related), chronic exposure to pesticides increases risk factors of epilepsy, a neurological disorder causing unprovoked, reoccurring seizures.
Mental Health Awareness Month, $3.1 million raised for epilepsy research, and more in this CURE Epilepsy Update.
Robot-assisted SEEG significantly reduced the duration of surgery (STS and TPT) compared to SDE implantations.
There is potential for epilepsy surgery to provide clinically meaningful improvements in quality of life.
Pediatric Epilepsy
While eyelid myoclonia is the disease hallmark, other seizure types, including absence seizures and generalized tonic-clonic seizures, may be present. It is thought to have a genetic etiology, and around one-third of patients may have a positive family history of epilepsy. Recently, specific genetic mutations have been recognized in a minority of patients.
We found a substantially lower proportion of patients with newly diagnosed epilepsy remained untreated compared to previous estimates from administrative data analysis.
Genetics
“It shows that epilepsies that are not usually inherited can still be genetic in their mechanism. And the specific genetic pathway we have identified, RAS/MAPK, opens a whole new avenue of therapeutic possibilities, since anti-cancer drugs that target this pathway may have unexpected uses in epilepsy,” Walsh said.
Long-term treatment with soticlestat was found to reduce seizure frequency by more than 50% in most Dravet syndrome patients, according to about two years of data from the ongoing ENDYMION 1 clinical trial.
