Pediatric Epilepsy
The FDA has approved abbreviated new drug applications to immediately market a generic version of clobazam (Onfi) (Lundbeck) tablets, CIV, 10 mg and 20 mg, and clobazam oral suspension, CIV, 2.5 mg/mL, for adjunctive treatment of seizures associated with Lennox-Gastaut Syndrome in patients 2 years of age and older.
Clobazam oral soluble film may improve adherence, reduce likelihood of dosing error, and provide more accurate dosing than currently available formulations of clobazam.
People with epilepsy have elevated self-harm risk, especially in the first year following diagnosis.
The Post-Traumatic Epilepsy Initiative is a team science, multi-disciplinary program that will expand the knowledge around the types of injuries that predispose the brain to epilepsy, as well as a develop new models to study epilepsy that results from injury.
SUDEP
Congenica announced a key partnership with the UK’s Epilepsy Society to study the genomics of sudden unexpected death in epilepsy (SUDEP).
Pediatric Epilepsy
Children with staring spells who were referred to a new-onset seizure (NOS) clinic were found to have epileptic seizures about half the time, according to findings presented at the Child Neurology Society annual meeting.
Researchers propose a straightforward protocol for heart rate variability evaluation, involving 5?minute measurements of root mean square of successive differences in wakefulness and light sleep.
50% of the royalties from A Mind Unraveled, Kurt Eichenwald's new memoir, will benefit CURE.
Genetics, Pediatric Epilepsy
A research team has discovered a new genetic cause for epileptic encephalopathy, a severe, difficult-to-treat childhood epilepsy syndrome.