Patients with epilepsy have a high risk of accidents and injuries, resulting in minimized physical activity and social withdrawal. Therefore, we surveyed the types of injuries that adult and paediatric patients with epilepsy may endure, the factors that may increase the risk of injuries, the clinical outcomes, and the limitations the patients may encounter because of traumas.
We demonstrated the significant impact that the COVID-19 pandemic had on epilepsy care. These results support those of previous studies and clarify the effect size of each pandemic-related factor on epilepsy care.
This study aimed to explore whether the time from stroke to epilepsy onset was related to the risk of drug resistance in patients with poststroke epilepsy (PSE).
Results showed that all ED visits, including seizure-related ones, decreased among all age groups and sexes during the pandemic period from April 1 to Dec. 29, 2020, compared with the same period in 2019. The largest decline in seizure-related ED visits, noted as early as February 2020, was observed among children aged 0 to 9 years.
To evaluate whether folic acid supplementation was associated with primary outcomes such as preterm birth (gestational age <37 weeks at birth), small for gestational age (SGA), and preeclampsia, investigators evaluated 100,105 singleton pregnancies from 1999-2008.
"For years, the blood-brain barrier has seemed like an insurmountable hurdle to the efficient delivery of biologics to the brain. Our work, using the latest in viral vector technology, proves that this is no longer the case; in fact, it is possible that under certain circumstances, the blood-brain barrier may actually prove to be therapeutically beneficial, serving to prevent 'leak' of therapeutics into the rest of the body."
Lacosamide monotherapy for the treatment of childhood epilepsy with centrotemporal spikes was well tolerated and resulted in significantly reduced seizures, according to a study published in Brain and Development.
Epidemiologic studies have investigated whether social deprivation is associated with a higher incidence of epilepsy and results are conflicting, especially in children.
Nonadherence to anti-seizure drugs (ASMs) is a significant problem in pediatric epilepsy and is linked to increased morbidity, mortality, clinically unnecessary medication changes, and increased healthcare costs.
