To evaluate whether folic acid supplementation was associated with primary outcomes such as preterm birth (gestational age <37 weeks at birth), small for gestational age (SGA), and preeclampsia, investigators evaluated 100,105 singleton pregnancies from 1999-2008.
"For years, the blood-brain barrier has seemed like an insurmountable hurdle to the efficient delivery of biologics to the brain. Our work, using the latest in viral vector technology, proves that this is no longer the case; in fact, it is possible that under certain circumstances, the blood-brain barrier may actually prove to be therapeutically beneficial, serving to prevent 'leak' of therapeutics into the rest of the body."
Lacosamide monotherapy for the treatment of childhood epilepsy with centrotemporal spikes was well tolerated and resulted in significantly reduced seizures, according to a study published in Brain and Development.
Find information on our 2021 Catalyst Award grantees, call for abstract submissions and letters of intent, and more.
Epidemiologic studies have investigated whether social deprivation is associated with a higher incidence of epilepsy and results are conflicting, especially in children.
Nonadherence to anti-seizure drugs (ASMs) is a significant problem in pediatric epilepsy and is linked to increased morbidity, mortality, clinically unnecessary medication changes, and increased healthcare costs.
Featuring the research of former CURE Epilepsy grantee Dr. John Swann. This exciting study, published in the Annals of Neurology, has the potential to transform the treatment landscape for babies with infantile spasms.
To investigate differences in long-term survival and short-term neurological deficits in adult patients fulfilling either sub-criterion of the Salzburg Consensus Criteria (SC) for non-convulsive status epilepticus (NCSE).
Adults with Dravet syndrome commonly experience walking difficulties that tend to worsen with age, a small study reports.
