Researchers engineered an electronic drug delivery tool that pumps seizure-stopping molecules directly to the source of the problem in the brain.
Researchers have successfully demonstrated how an electronic device implanted directly into the brain can detect, stop and even prevent epileptic seizures.The researchers, from the University of Cambridge, the École Nationale Supérieure des Mines and INSERM in France, implanted the device into the brains of mice, and when the first signals of a seizure were detected, delivered a native brain chemical which stopped the seizure from progressing.
On Nov. 19, Susan and David Axelrod will join scientists, researchers and community members for the 2018 Leaders in Innovation Dinner hosted by Robarts Research Institute. This year’s dinner celebrates research excellence in the field of epilepsy.
Pediatric Epilepsy
Status epilepticus is not an uncommon neurologic emergency and depending on the associated etiology can carry significant morbidity, mortality, and cost especially if treatment is not performed in a timely manner.
SUDEP
1.11 out of 1,000 children with epilepsy die suddenly each year, according to a Canadian study by CURE grantee Dr. Elizabeth Donner.
Pediatric Epilepsy
Febrile seizures may increase the risk for subsequent epilepsy in children. Recurrent febrile seizures increased the cumulative incidence of epilepsy.
Heartbeat irregularities connected to brain activity abnormalities may lead to the ability to predict eventual epileptic seizures in subjects who suffered physical or infectious brain injuries.
SUDEP
No distinguishable autopsy findings were found between SUDEPs and epilepsy-related drownings when there were no drowning-related signs and no clear evidence of submersion.
ZX008 provided reduction in convulsive seizure frequency in the majority Lennox-Gastaut syndrome patients and was generally well tolerated.
