Sympazan™ (clobazam) oral film received tentative approval by the FDA for the adjunctive treatment of seizures associated with Lennox-Gastaut Syndrome (LGS) in patients 2 years of age or older.
Our data suggest that hormone therapy for assisted reproduction could exacerbate seizures and should be carefully monitored in women with epilepsy, especially those taking drugs inactivated by glucuronidation. Adjunctive concomitant antiepileptic therapy should be considered.
Ketogenic Diet
Studies that used objective neuropsychological tests confirmed benefits on alertness but found no improvement in global cognition. There are indications that these improvements are caused by both seizure reduction and direct effects of KD on cognition.
Researchers engineered an electronic drug delivery tool that pumps seizure-stopping molecules directly to the source of the problem in the brain.
Researchers have successfully demonstrated how an electronic device implanted directly into the brain can detect, stop and even prevent epileptic seizures.The researchers, from the University of Cambridge, the École Nationale Supérieure des Mines and INSERM in France, implanted the device into the brains of mice, and when the first signals of a seizure were detected, delivered a native brain chemical which stopped the seizure from progressing.
On Nov. 19, Susan and David Axelrod will join scientists, researchers and community members for the 2018 Leaders in Innovation Dinner hosted by Robarts Research Institute. This year’s dinner celebrates research excellence in the field of epilepsy.
Pediatric Epilepsy
Status epilepticus is not an uncommon neurologic emergency and depending on the associated etiology can carry significant morbidity, mortality, and cost especially if treatment is not performed in a timely manner.
SUDEP
1.11 out of 1,000 children with epilepsy die suddenly each year, according to a Canadian study by CURE grantee Dr. Elizabeth Donner.
Pediatric Epilepsy
Febrile seizures may increase the risk for subsequent epilepsy in children. Recurrent febrile seizures increased the cumulative incidence of epilepsy.