ZX008 provided reduction in convulsive seizure frequency in the majority Lennox-Gastaut syndrome patients and was generally well tolerated.
Quality-of-life improvements for people with epilepsy depend more upon addressing psychiatric symptoms than seizures themselves.
Identifying barriers to successful delivery of effective epilepsy transition care is critical to remediating treatment care gaps and building effective future care models.
Pediatric Epilepsy
In children with brain tumors, higher seizure frequency with normal neurologic examination was more prevalent in benign tumors, whereas less frequent seizures with focal weakness and signs of increased intracranial pressure were more indicative of malignancy. Delayed onset of seizures was more often observed in the children with malignant brain tumors. Seizure characteristics play an important role in relation to tumor biology and epileptogenesis in pediatric brain tumors.
SUDEP
Mutations associated with Dravet syndrome in mice led to irregularities in the heart muscle's sodium channels.
This study is investigating whether Lacosamide (Vimpat®)—when taken with current anti-epileptic medicine—helps decrease the number of seizures patients experience
Investigators are testing the feasibility and acceptability of this study's procedures, measures and of the YESS! web-based intervention.
This study estimates the cost of admissions related to status epilepticus in the USA to be approximately $7000 in children and $13,000 in adults, and quantifies how costs markedly increase once status epilepticus becomes super-refractory.
