Contributors to the work include numerous CURE Epilepsy advisors, grantees, and staff. The aim of the CDEs is to improve the standardization of experimental designs across a range of epilepsy research-related methods.
"If we can figure out what brain changes make people have functional seizures, we can begin to look at how we can change that back," said first author Wesley Kerr, M.D., Ph.D., a neurologist and epileptologist at University of Michigan Health.
The University of Toronto's Xilin Liu is working with microelectronics and artificial intelligence to make this emerging technology both safer and smarter.
The Loulou Foundation, a private foundation dedicated to the development of therapeutics for the neurodevelopmental condition CDKL5 Deficiency Disorder (CDD), announced today that the first patient has been enrolled in the three-year observational study with CDD patients, the Clinical Assessment of NeuroDevelopmental measures In CDD (CANDID) study.
Patients with psychogenic non-epileptic seizures (PNES) report greater frequency of childhood trauma than patients with epilepsy. This effect appears to hold across all trauma types, with no strong evidence emerging for a particular trauma type that is more prevalent in PNES.
Genetics
In this new effort, the researchers sought to learn if the variant responsible for febrile epilepsy had arisen in multiple people over time or if it could be traced back to just one person.
Our results reveal that several ASMs (e.g. topiramate, oxcarbazepine, benzodiazepines) are prescribed “off-label” in distinct scenarios of young children with epilepsy. In addition, recent scientific guidelines were not always adopted by several survey respondents, suggesting a potential knowledge gap.
Featuring the work of CURE Epilepsy grantee Dr. John Swann. Our goal was to determine whether animals with a history of epileptic spasms have learning and memory deficits.
This report may be used as an illustrative tool for teaching epilepsy syndromes and as a practical and comprehensive aid for the classification of epilepsy individuals' syndromes.