his study suggests that a shorter duration yet deeper therapeutic coma as treatment for refractory status epilepticus may be more effective and safer than the currently recommended duration of 24?48 hours.
This study found a rate of 13.6% for late seizure recurrence after weaning from at least one antiseizure drug in patients with new onset status epilepticus.
Initial findings suggest that valproate can affect the function of the human placenta during early pregnancy.
40% of people with epilepsy report they sometimes or often forget to take their AED as scheduled, and about 30% report they consciously chose not to follow the AED treatment plan.
Patients with anti-LGI1 or anti-GABABR antibodies have a higher risk of developing persistent seizures.
Neuroimaging results indicate that left anterior temporal resections constrain development of verbal cognition, whereas simultaneously cortical growth after surgical treatment can support improvements in IQ.
The objective of this study was to measure the psychosocial burden for persons with epilepsy and for their spouses and to compare and correlate this with the clinical burden of seizures.
The risk of hyperammonemia is almost 40% in patients receiving intravenous valproic acid in the ICU setting.
Upon its preliminary review, the FDA determined that the NDA was not sufficiently complete to permit a substantive review.
