Pediatric Epilepsy
A study characterizes non-convulsive seizures in a mouse model of Dravet syndrome and identifies the brain area that could be targeted to stop them.
This paper discusses the advantage and limitations of screening tools and makes a compelling argument for neurologists to take an active role in the diagnosis and treatment of common psychiatric comorbidities in patients with epilepsy.
This paper explores the nature of psychiatric comorbidities in people with an intellectual disability who have epilepsy.
This study finds that grafting certain cells derived from human-induced pluripotent stem cells into the brain can help alleviate seizures, as well as improve brain function, in rats modeling temporal lobe epilepsy.
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Death certification in status epilepticus is likely to be an underestimate of the reality. Further efforts are urgently needed to determine the extent of status epilepticus-related deaths and all deaths in patients with epilepsy.
The trial achieved its primary endpoint of safety and tolerability and showed OV935 was generally well tolerated.
Genetics, Pediatric Epilepsy
A round-up of the top epilepsy research news from the past month.
RogCon and The Florey Institute of Neuroscience presented preclinical data on the company's lead program, RC-222, an antisense oligonucleotide designed to down-regulate SCN2A.