A study provides potential new targets for treating epilepsy and novel fundamental insights into the relationship between neurons and their glial "helper" cells.
Pediatric Epilepsy
Researchers have discovered that a drug commonly used to treat multiple sclerosis may, after necessary modifications, one day be used to treat patients with epilepsy.
Genetics
Future gene therapies for genetic causes of neurodevelopmental disorders such as autism spectrum disorder, intellectual disability, and epilepsy, may also be effective in adult patients.
Pediatric Epilepsy
Without understanding how the disease creates burden for the patient (or family), it is difficult to know how to assess the impact of treatment.
Pediatric Epilepsy
The data suggests that in juvenile myoclonic epilepsy (JME), seizure control is linked to seizure type, possibly allowing a more individualized approach when counselling JME patients.
CBD
Cannabidiol may have beneficial effects on quality of life and mood that are independent of treatment response.
Genetics, Pediatric Epilepsy
This study further expands the genotypic and phenotypic spectrum of epilepsies associated with GABRG2 variants.
These results indicate that the seizures of temporal lobe epilepsy can be effectively inhibited by ultrasound stimulation, and this effect is independent of ultrasound type (pulsed or continuous).
Pediatric Epilepsy
Interictal spike propagation is a highly reproducible output of epileptic networks. These findings shed new light on the spatiotemporal dynamics that may constrain the network mechanisms of refractory epilepsy.