Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results from the Atherosclerosis Risk in Communities Study

November 14, 2018

In this cohort study of 10,420 adults, researchers investigated the midlife vascular and lifestyle risk factors for late-onset epilepsy. Outcomes suggest an association of hypertension, diabetes, smoking, APOE ?4 allele number, activity level, and alcohol use with late-onset epilepsy. They identified that stroke and dementia were associated with late-onset epilepsy, however, vascular and lifestyle risk factors remained significant even in the absence of stroke or dementia.