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Citizens United for Research in Epilepsy (CURE), is the leading nongovernmental agency fully committed to funding research in epilepsy.

The organization was founded by Susan Axelrod and a small group of parents of children with epilepsy who were frustrated with their inability to protect their children from seizures and the side effects of medications. Unwilling to sit back, they joined forces to spearhead the search for a cure.

Since its inception in 1998, CURE has been at the forefront of epilepsy research, raising more than $60 million to fund research and other initiatives that will lead the way to a cure for epilepsy. CURE funds grants for young and established investigators and has awarded more than 230 cutting-edge projects in 15 countries around the world to date.

CURE has led a dramatic shift in the epilepsy research community from simply treating seizures to enhancing understanding of underlying mechanisms and causes, so that cures and preventative strategies can be found. CURE’s research program is cutting-edge, dynamic and responsive to new scientific opportunities and directions through both investigator-initiated grants and unprecedented scientific programs and initiatives.

Tireless in its efforts and determination, we won’t stop until a CURE is found for epilepsy.

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April 8, 2019

Citizens United for Research in Epilepsy Appoints Beth Lewin Dean as Chief Executive Officer

Beth brings 17 years of extensive experience within the epilepsy field, which has been driven by her strong commitment to understanding the needs, aspirations and hopes of patients and their loved ones.  

March 28, 2019

Citizens United for Research in Epilepsy (CURE) receives $2M gift from Shery and David Cotton and Lisa and Michael Cotton.

This gift benefits CURE and its initiatives to find a cure for epilepsy.

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January 30, 2019

Citizens United for Research in Epilepsy (CURE) Launches Podcast, Seizing Life

Kelly Cervantes, CURE board member and wife to HAMILTON Chicago star, to host and reveal the everyday stories of those impacted by epilepsy

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January 17, 2019

CURE Discovery: Predicting Acquired Epilepsy Following a Brain Infection

Researchers identify a possible biomarker, detectable as early as 14 weeks before the first seizure, for predicting who will develop epilepsy following infection with malaria.

December 4, 2018

New CURE-Funded Research Projects

Announcing the next round of promising epilepsy research projects funded by the CURE Taking Flight and Innovator Awards! Read on to learn about our latest grantees and their studies.

October 24, 2018

Announcing the 2018 Post-Traumatic Epilepsy Initiative Grantees

The Post-Traumatic Epilepsy Initiative is a team science, multi-disciplinary program that will expand the knowledge around the types of injuries that predispose the brain to epilepsy, as well as a develop new models to study epilepsy that results from injury.

August 21, 2018

Clinical Trial: A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications (VALOR)

This study is investigating whether Lacosamide (Vimpat®)—when taken with current anti-epileptic medicine—helps decrease the number of seizures patients experience

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August 18, 2018

Mayor Emanuel Interviews Singer, Actor and “Hamilton” Star Miguel Cervantes on “Chicago Stories”

On this week’s episode of “Chicago Stories” the star of Chicago’s “Hamilton” Miguel Cervantes gives Mayor Emanuel his take on the smash-hit musical, shares the story of his hard-won career, and talks about his biggest role of all as “Dad” and raising awareness for childhood epilepsy.

August 16, 2018

Hari Ravichandran Launches Foundation With Inaugural Gift To Citizens United for Research in Epilepsy (CURE)

$150,000 Commitment in Support of 20th Annual Benefit and ‘Taking Flight’ Research Award

July 10, 2018

Students Impacted by Epilepsy Use Scholarships to Become Agents of Change Across the US

Citizens United for Research in Epilepsy (CURE) and Lundbeck have announced the newest cohort of Education Enrichment Fund (EEF) Scholars for 2018. These 10 new scholars have all been personally impacted by epilepsy and, collectively, will receive nearly $50,000 to advance their education while bringing greater awareness to epilepsy.The EEF Scholarships—made possible by generous support from Lundbeck—award a one-time scholarship (up to $5,000) to those living with epilepsy, or for family members and caregivers of those impacted by the disease. The scholarship, which is in its third year, covers tuition, books, and academic materials and supports coursework advancing personal knowledge in research, health education and advocacy in relation to epilepsy.“As a patient-centered and research driven organization, CURE greatly appreciates Lundbeck’s generous support of the Education Enrichment Fund Scholars Program,” said Stacey Pigott, Chair of CURE’s Research Committee. “This year’s recipients are all incredibly deserving with their personal connection to epilepsy and shared goal of furthering their education to enact positive change within the broader epilepsy community.”One scholar, after serving as a nurse for seven years in the U.S. Army, was diagnosed with epilepsy caused by a brain tumor. Her personal battle towards recovery has led her to pursue a career as a Psychiatric Mental Health Nurse Practitioner.Another scholar has spent ten years battling for her son who was diagnosed with epilepsy at the age of four. Her triumphs and tragedies have motivated her to pursue a career as a Family Nurse Practitioner so she can advocate for others who are battling this disorder.Other awardees include an aspiring pediatric neurologist seeking to combat the effects of epilepsy he has witnessed in his older brother; a student living with epilepsy himself and striving to become a neurologist; and a teacher in the peace corps seeking to advance epilepsy research to treat not only her own disorder, but the disorder of the students in her classroom.“This is the third round of Education Enrichment Fund Scholars and, once again, I am amazed at the recipients’ passion, hopefulness and determination to make a difference in the lives of others who are living with epilepsy,” said Lorena Di Carlo, Vice President & General Manager, Neurology, at Lundbeck. “This initiative has taught us so much about the strength of the epilepsy community, and we are proud to be a part of it.”Launched in 2016 with just three scholars, the EEF Scholarship program has more than tripled in 2018 and has supported nearly 20 scholars since the program’s inception. 2018 winners include:Brook Hodgeman - St. Albans, VT Devin Leishman - Manhattan, KS Cote Licciardi - Hammond, LA Michelle Mottern - Auburndale, FL Rachel Simms - Concord, CA Daniel Stanley - Wauconda, IL Matthew Summerfield - Saginaw, MI Daniel Torolira - Los Angeles, CA Derek Vielhauer - Dublin, CA Logan Welborn - Winston Salem, NC Click to learn more about each scholar.###About CUREThe mission of Citizens United for Research in Epilepsy (CURE) is to find a cure for epilepsy, by promoting and funding patient-focused research.  Since its inception in 1998, CURE has raised over $50 million to advance its goal of no seizures and no side effects. To date, CURE has awarded more than 220 cutting-edge research projects in 15 countries around the world. CURE is the leading nongovernmental agency fully committed to funding research in epilepsy.For information about CURE, please visit our website at www.CUREepilepsy.org or contact us at info@CUREepilepsy.org.About LundbeckH. Lundbeck A/S (LUN.CO, LUN DC, HLUYY) is a global pharmaceutical company specialized in psychiatric and neurological disorders. For more than 70 years, we have been at the forefront of research within neuroscience. Our key areas of focus are depression, schizophrenia, Parkinson's disease and Alzheimer's disease. An estimated 700 million people worldwide are living with psychiatric and neurological disorders and far too many suffer due to inadequate treatment, discrimination, a reduced number of working days, early retirement and other unnecessary consequences. Every day, we strive for improved treatment and a better life for people living with psychiatric and neurological disorders — we call this Progress in Mind.Read more at www.lundbeck.com/global/about-us/progress-in-mind.Our approximately 5,000 employees in more than 50 countries are engaged in the entire value chain throughout research, development, production, marketing and sales. Our pipeline consists of several late-stage development programs and our products are available in more than 100 countries. Our research center is based in Denmark and our production facilities are located in Denmark, France and Italy. Lundbeck generated revenue of DKK 17.2 billion in 2017 (EUR 2.3 billion; USD 2.6 billion).In the U.S., Lundbeck employs nearly 1,000 people focused solely on accelerating therapies for brain disorders. With a special commitment to the lives of patients, families and caregivers, Lundbeck U.S. actively engages in hundreds of initiatives each year that support our patient communities. For additional information, we encourage you to visit our corporate site at www.lundbeck.com/us and connect with us on Twitter at @LundbeckUS.

January 22, 2018

Stopping Acquired Epilepsy Before It Starts? CURE Researcher Identifies a Possible Biomarker

Early intervention, in response to rising biomarker levels, could delay the onset of epilepsy, block the progression of the disease, and eliminate impairments in memory (Chicago - February 6, 2018) New research, funded by Citizens United for Research in Epilepsy (CURE), has discovered a ‘smoking gun’ biomarker that could result in treatments that stop some epilepsies before they even start.“Being able to identify that a person is likely to develop epilepsy following a brain injury is one of the most important focus areas in modern-day epilepsy research,” says Dr. Laura Lubbers, CURE’s Chief Scientific Officer. “With 3.4 million Americans suffering from epilepsy and seizures in the U.S., this discovery of a predictive biomarker for a certain form of epilepsy could prevent unpredictable seizures from taking over the lives of millions of Americans and their families.”Using a rat model of brain injury and epilepsy, CURE-funded researcher Dr. Annamaria Vezzani and her team at the Mario Negri Institute for Pharmacological Research in Milan, Italy have identified that, prior to the development of epilepsy, high levels of the protein high-mobility group box 1 – also known as HMGB1 – have been found in both the brain and blood of rats. This means that high levels of the biomarker HMGB1 may predict the impending onset of epilepsy.The CURE-funded research team also discovered that a combination of existing medications not only prevent an increase in HMGB1 levels, but delay the onset of epilepsy, halt the disease’s progression, and eliminate memory impairments associated with epilepsy.“This discovery suggests that early intervention could slow, or potentially stop, the development of epilepsy in those at risk,” says Dr. Lubbers. “Epilepsy costs the United States approximately $15.5 billion each year, and prevention could result in ripple effects that go far beyond the millions who may receive early treatment.”HMGB1 is normally released in the brain in response to neuroinflammation, the brain’s response to injury. Targeting the neuroinflammation that leads to increased HMGB1 with drugs that are already in clinical use could create an entirely new therapeutic area to prevent epilepsy from developing or improve its outcomes.“With this research, Dr. Vezzani and her team have provided hope that a treatment for preventing acquired epilepsy before it occurs is on the horizon,” says CURE CEO Kate Carr. “We thank both Dr. Vezzani as well as our supporters who have made such research possible through their generous donations.”

November 29, 2017

CURE Taking Flight and Innovator Awards accepting applications

CURE is now accepting LOIs for its first 2018 grant cycle. These grants include:Innovator Award - A grant of $50,000 paid over one year Taking Flight Award - A grant of $100,000 paid over one year The deadline for both of these grants is January 8, 2018 at 9pm Eastern.Full Key Cycle 1 timeline details are below:Activity DateLetter of Intent Deadline Monday, January 8th, 2018 - 9pm ETFull Application Invitations Wednesday, February 21st, 2018Full Application Deadline Wednesday, March 28th, 2018 - 9pm ETAnticipated Award Announcement July 2018Anticipated Project Start Date September 2018 For more information or to apply, interested parties should visit CURE's Grant Opportunities webpage.

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