2005
CURE Epilepsy Award, Funded by the Hope Foundation
Controlling Epileptogenicity In Human Focal Cortical Dysplasia
Massimo Avoli, MD, PhD
McGill University
Focal Cortical Dysplasia (FCD) is a structural abnormality in the brain, which can lead to seizures, which do not respond to pharmacological treatment. In a second year of CURE funding, Dr. Avoli will be testing the hypothesis that gap-junctions in patients with FCD contribute to seizures and whether repetitive electrical stimulation of FCD networks can prevent seizures.