Molecular Mechanism Of Limbic Epilepsy In A New Genetic Mouse Model

Yan Yang, PhD
The Jackson Laboratory, Maine

Mouse models of epilepsy have contributed to the discovery of human epilepsy genes and all antiepileptic drugs to date. Dr. Yang has identified a new gene (BRUNOL4), which plays a role in a type of epilepsy originating in the temporal lobe. He will investigate how a deficiency in this gene leads to recurrent seizures in mice, and evaluate novel anti-epileptic therapies using this new mouse model of epilepsy.

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