There is a higher likelihood of the development of post-stroke epilepsy (PSE) in patients who had longer duration of early-onset post-stroke status epilepticus (PSSE), according to a study published in Seizure.
Patients with early-onset acute PSSE who were admitted to Vall d’Hebron University Hospital in Barcelona, Spain, between February 2011 and April 2017 were included in the study (N=117). Exclusions included previous history of epilepsy, arteriovenous malformation, subarachnoid hemorrhage, and subdural hematoma. Patients underwent neuroimaging of the brain with CT or MRI scans and were clinically monitored during the acute/subacute phase of the stroke.
Recorded stroke-related variables included the affected artery territory, type and severity of stroke according to the National Institutes of Health Stroke Scale (NIHSS) score, and lesion size and etiology. Other variables included were demographic characteristics, smoking and alcohol use, psychiatric history, cognitive impairment, and functional disability at discharge after stroke. After 2015, the PSSE features recorded were timing from stroke at PSSE onset, NIHSS score at time of status epilepticus, and status epilepticus type, duration, and treatment.