This article reviews the implications of uncontrolled epilepsy, including direct and indirect costs, as well as other factors that contribute to epilepsy-related healthcare resource utilization and the broader economic impact of the disease. In addition to examining the effects of the disease on quality of life and challenges to disease management, this article explores potential areas of focus to reduce healthcare resource utilization related to epilepsy care, including access to newer antiepileptic drugs, adherence to treatment regimens, and the impact of titration and maintenance regimens.
The article concludes that significant unmet needs remain for patients with epilepsy, particularly those with uncontrolled epilepsy. Uncontrolled epilepsy is associated with a substantially greater burden in patient quality of life as well as healthcare costs. Achieving seizure control requires an individualized approach to care that encompasses the substantial burden of disease for patients. Ensuring timely interventions through improved access to appropriate antiepileptic drugs regimens may not only reduce healthcare resource utilization, but also improve the lives of individuals with epilepsy.