February 24, 2023

New Method Finds Epilepsy-Causing Neural “Hubs” in Children

Article published by Inside Precision Medicine

A new, very precise, method of determining which brain cells lead to epileptic episodes in children has been developed by a team at University of Texas at Arlington and collaborators. Currently, epilepsy surgery is the safest and most effective treatment for these patients and offers a 50% chance of eliminating seizures.

The team used noninvasive techniques and advanced computational methods to measure the electric and magnetic signals generated by neural cells and identify functional networks responsible for the generation of seizures in children with epilepsy.

“This could benefit so many children who can’t control epilepsy with drugs, which represents between 20 and 30% of children suffering from epilepsy,” said Christos Papadelis, senior author, who also serves as the director of research in the Jane and John Justin Neurosciences Center at Cook Children’s Health Care System.

The paper was published in Brain, and the lead author is Ludovica Corona. It was produced in collaboration with Boston Children’s Hospital, Massachusetts General Hospital, and Harvard Medical School.