Talk summary: Individuals with epilepsy, particularly those with uncontrolled epilepsy, are at a much greater risk of premature death than those without. In fact, the standardized mortality ratio in those with epilepsy is between 2 and 3. In the UK, the most common cause of epilepsy-related death is due to Sudden Unexpected Death in Epilepsy (SUDEP), which accounts for up to one-fifth of deaths in some series. SUDEP is more common in those with frequent convulsive seizures (particularly nocturnal seizures) and in those with drug-resistant epilepsy. While the causes of SUDEP are unknown, the most commonly suggested underlying mechanisms are cardiac arrhythmias, respiratory depression and “cerebral shutdown.” Because no preventative measures currently exist, an understanding of SUDEP risk factors, potential mechanisms and the effectiveness of preventative measures is essential. To this end, there are a multitude of opportunities available in the field of SUDEP research and these opportunities will be interactively discussed during the presentation.
March 20, 2019
Daylight Saving Time Transitions are Not Associated with Increased Seizure Incidence
Despite expectations that circadian and sleep disruption related to daylight savings time transitions would increase the incidence of seizures, this study found little substantive evidence for such an association in this large, longitudinal cohort.
March 20, 2019
Literature Review Shows There is a Lack of Understanding of SUDEP for People with Epilepsy and Their Relations
Findings show the conflicting perceptions, feelings, and thought processes that occur in learning about and deciding to discuss SUDEP as a healthcare provider, person with epilepsy, or family/friend of a person with epilepsy.