Talk summary: Individuals with epilepsy, particularly those with uncontrolled epilepsy, are at a much greater risk of premature death than those without. In fact, the standardized mortality ratio in those with epilepsy is between 2 and 3. In the UK, the most common cause of epilepsy-related death is due to Sudden Unexpected Death in Epilepsy (SUDEP), which accounts for up to one-fifth of deaths in some series. SUDEP is more common in those with frequent convulsive seizures (particularly nocturnal seizures) and in those with drug-resistant epilepsy. While the causes of SUDEP are unknown, the most commonly suggested underlying mechanisms are cardiac arrhythmias, respiratory depression and “cerebral shutdown.” Because no preventative measures currently exist, an understanding of SUDEP risk factors, potential mechanisms and the effectiveness of preventative measures is essential. To this end, there are a multitude of opportunities available in the field of SUDEP research and these opportunities will be interactively discussed during the presentation.
June 22, 2021
The Use of Computational Models in the Management and Prognosis of Refractory Epilepsy: A Critical Evaluation
Advances in computational models may in the future significantly increase the application and efficacy of surgery for patients with drug-resistant epilepsy by optimizing the site and amount of cortex to resect.
June 21, 2021
The ‘Mozart Effect’ Shown to Reduce Epileptic Brain Activity, New Research Reveals
Experts believe the study’s findings could pave the way for individualized music therapies to be developed to prevent and control epileptic seizures in the future and have called for more research into the effects of music on the brain.