As part of our Meet the Moment initiative, Protecting Our Progress Awards provide emergency support to researchers facing immediate threats to their work due to federal funding uncertainty and policy-related constraints, helping ensure critical epilepsy research continues uninterrupted.
What if epilepsy could be treated, rather than simply controlled? For millions of people living with epilepsy, medication is a lifelong necessity. Yet even when drugs control seizures, the disease remains, often accompanied by debilitating problems with memory and thinking.
This research challenges the idea that epilepsy must be treated forever.
Dr. Roopra and his team have discovered that a short course of an existing anti-inflammatory drug can dramatically reduce seizures and restore memory in mice with established epilepsy. Remarkably, these improvements persist for months after treatment ends. With support from CURE Epilepsy, the team aims to uncover how this remarkable recovery occurs and determine whether other existing drugs can achieve the same lasting benefits.
Dr. Roopra’s ultimate goal is to move beyond lifelong seizure suppression toward treatments that fundamentally change the course of epilepsy—giving people not just fewer seizures, but the possibility of a life free from them: No seizures, no side effects.