2010

Funded by the Christopher Donalty and Kyle Coggins Memorial Award

Prevention Of SUDEP By Serotonergic Agents In DBA/1 Mice

Carl Faingold, PhD
Southern Illinois University School of Medicine
 

Dr. Faingold has developed a new animal model of human sudden unexpected death in epilepsy (SUDEP), DBA/1 mice. These animals show generalized seizures and then stop breathing if not resuscitated, which is common in human SUDEP. They found that drugs that increase the level of a neurochemical (serotonin) in the brain will prevent SUDEP in these mice. The current study will examine if new drugs that have a more selective effect on serotonin will prevent the respiratory arrest that follows seizures in these mice.

    STAY UP TO DATE

    Join our email list for the
    latest epilepsy research news,
    discoveries, and more.