Low-frequency fiber-tract stimulation of the corpus callosum suppresses both cortical and cortically induced hippocampal seizures in an acute model of focal cortical seizures. The stimulation paradigm is selective, as it is only effective when targeted to specific regions of the corpus callosum that project maximally to cortical regions generating the seizure activity. Selective placement of stimulation electrodes along the corpus callosum could be used as a patient-specific treatment for cortical epilepsies.
October 28, 2020
Recognizing and Refuting the Myth of Tongue Swallowing During a Seizure
There is a harmful myth that persists in modern culture that one should place objects into a seizing person’s mouth to prevent “swallowing the tongue.” Despite expert guidelines against this, the idea remains alive in popular media and public belief. The authors of this study aimed to investigate the myth’s origins and discredit it.
October 27, 2020
Characteristics and Treatment Outcomes of Newly Diagnosed Epilepsy in Older People: A 30-Year Longitudinal Cohort Study
This study sought to describe the clinical characteristics and evaluate the long-term treatment outcomes in older people with newly diagnosed epilepsy over the past 30 years.
October 26, 2020
Generalized, Focal, and Combined Epilepsies in Families: New Evidence for Distinct Genetic Factors
A recent study suggests that distinct genetic influences underlie the recently recognized entity of combined epilepsies, just as generalized epilepsies and focal epilepsies each have distinct genetic influences. Its conclusions have important implications for molecular genetic studies aimed at identifying genetic determinants of the epilepsies.