Low-frequency fiber-tract stimulation of the corpus callosum suppresses both cortical and cortically induced hippocampal seizures in an acute model of focal cortical seizures. The stimulation paradigm is selective, as it is only effective when targeted to specific regions of the corpus callosum that project maximally to cortical regions generating the seizure activity. Selective placement of stimulation electrodes along the corpus callosum could be used as a patient-specific treatment for cortical epilepsies.
November 13, 2018
January 27, 2023
Frequency of and Factors Associated with Antiseizure Medication Discontinuation Discussions and Decisions in Patients with Epilepsy: a Multicenter Retrospective Chart Review
Only approximately half of patients with prolonged seizure-freedom had a documented discussion about antiseizure medication discontinuation. Discontinuation was fairly rare even among low-risk patients.